What do systematic reviews say?

Titrated oxygen therapy vs high‐flow oxygen therapy

Titrated oxygen therapy may leads to lower mortality (respiratory‐ related and all‐cause compared with high‐flow oxygen therapy (low certainty).

• Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  RR 0.22 [0.05, 0.97]
  1 study · 214 participants
  Low

Titrated oxygen therapy vs high‐flow oxygen therapy

• Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 214 participants
  Low

Titrated oxygen therapy vs high‐flow oxygen therapy

Titrated oxygen therapy showed no clear difference in ventilation of any type compared with high‐flow oxygen therapy (low certainty).

• Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  RR 0.67 [0.29, 1.55]
  1 study · 189 participants
  Low

Titrated oxygen therapy vs high‐flow oxygen therapy

• Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 214 participants
  Low

Titrated oxygen therapy vs high‐flow oxygen therapy

The review found no eligible studies for this question.

• Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Titrated oxygen therapy vs high‐flow oxygen therapy

The review found no eligible studies for this question.

• Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Titrated oxygen therapy vs high‐flow oxygen therapy

The review found no eligible studies for this question.

• Oxygen therapy in the pre‐hospital setting for acute exacerbations of chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

• Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 90 participants
  Low

Intervention not reported

• Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  28 studies · 775 participants
  Low

Ambulatory oxygen vs air

• Ambulatory and short‐burst oxygen for interstitial lung disease 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

Ambulatory oxygen vs air

• Ambulatory and short‐burst oxygen for interstitial lung disease 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 6 participants
  Low

Ambulatory oxygen vs air

• Ambulatory and short‐burst oxygen for interstitial lung disease 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Low

Ambulatory oxygen vs air

• Ambulatory and short‐burst oxygen for interstitial lung disease 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 72 participants
  Low

Exercise vs control

• Exercise‐based rehabilitation programmes for pulmonary hypertension 2023 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 314 participants
  Low

Pulmonary rehabilitation vs usual care

• Pulmonary rehabilitation versus usual care for adults with asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 129 participants
  Very low

Nebulised magnesium sulfate + standard care vs placebo + standard care

• Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Very low

Magnesium sulfate vs ipratropium

The review found no eligible studies for this question.

• Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intravenous magnesium sulfate + standard care vs placebo + standard care

• Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 77 participants
  Very low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 271 participants
  Moderate
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 171 participants
  Low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 234 participants
  Low
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 170 participants
  Low