Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

45 questions · 45 findings · 3 reviews

No studies found 14 · 31.1%GRADE not reported 0 · 0%Very low 15 · 33.3%Low 14 · 31.1%Moderate 2 · 4.4%High 0 · 0%

Nicotinamide vs clindamycin

Withdrawal for any reason (medium term: treatment duration from 5 to 8 weeks) · participants with acne

Nicotinamide showed no clear difference in withdrawal for any reason (medium term: treatment duration from 5 to… compared with clindamycin (low certainty).

1 finding from 1 review

Nicotinamide vs erythromycin

Withdrawal for any reason (medium term: treatment duration from 5 to 8 weeks) · participants with acne

Nicotinamide showed no clear difference in withdrawal for any reason (medium term: treatment duration from 5 to… compared with erythromycin (low certainty).

1 finding from 1 review

Nicotinamide plus tetracycline vs prednisone

Disease control: complete response at 8 weeks: excluding dropouts · bullous pemphigoid

It is very uncertain whether nicotinamide plus tetracycline changes disease control: complete response at 8 weeks: excluding dropouts compared with prednisone (very low certainty).

1 finding from 1 review

Azelaic acid vs adapalene

Participants' global self‐assessment of acne improvement · participants with acne

It is very uncertain whether azelaic acid changes participants' global self‐assessment of acne improvement Improved to… compared with adapalene (very low certainty).

1 finding from 1 review

Azelaic acid vs tretinoin

Participants' global self‐assessment of acne improvement Good to excellent improvement (long term: treatment duration > 8 weeks) · participants with acne

Azelaic acid showed no clear difference in participants' global self‐assessment of acne improvement Good to… compared with tretinoin (moderate certainty).

1 finding from 1 review