Azelaic acid vs tretinoin: Treatment withdrawal
- Population
- participants with acne
- Intervention
- Azelaic acid
- Comparison
- tretinoin
- Outcome
- Treatment withdrawal
Azelaic acid showed no clear difference in withdrawal for any reason (long term: treatment duration > 8 weeks) compared with tretinoin (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Azelaic acid vs tretinoin Withdrawal for any reason (long term: treatment duration > 8 weeks) · participants with acne Azelaic acid showed no clear difference in withdrawal for any reason (long term: treatment duration > 8 weeks) compared with tretinoin (low certainty). Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne (2020) · Cochrane Headline outcomes only | RR 0.66 [0.29, 1.47] | 2 studies · 309 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acne 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.