Patients with one or more adverse events · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…
Paracetamol (single oral dose, any dose or formulation; subgroups up… showed no clear difference in patients with one or more adverse events compared with placebo; GRADE not reported.
1 finding from 1 review
Oral cancer risk · People with and without more than 15 missing teeth
More than 15 missing teeth was associated with higher odds of oral cancer.
1 finding from 1 review
OR 1.91 [1.01, 3.62]
5 studies
GRADE not reported
Pain at 12 months or more (long-term postobturation pain) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
1 finding from 1 review
Early childhood caries (ECC) · Children younger than 71 months (under 6 years)
Breastfeeding for more than 12 months is associated with higher ECC prevalence (low certainty).
1 finding from 1 review
OR 1.86 [1.48, 2.35]
13 studies
Low
Early childhood caries (ECC) · Children younger than 71 months (under 6 years)
Breastfeeding for more than 24 months is associated with higher ECC prevalence (low certainty).
1 finding from 1 review
OR 2.99 [1.03, 8.67]
4 studies
Low
Early childhood caries (ECC) - incidence/risk · Children with exclusively primary dentition (age ≤71 months)
Breastfeeding beyond 24 months is associated with an increased risk (incidence) of early childhood caries versus not breastfeeding at the same age (RR 2.44, 95% CI 1.97 to 3.02; low certainty).
1 finding from 1 review
Early childhood caries experience (mean dmft) · Nigerian children with primary dentition (approximately 6 months to 5 years)
In primary dentition, high-frequency sugar consumption was associated with slightly higher, non-significant odds of caries (OR 1.13, 95% CI 0.23 to 5.44), with high heterogeneity (I2=83%; ungraded).
1 finding from 1 review
Dental caries in permanent teeth · Nigerian individuals with permanent dentition (approximately 12 years and older)
In permanent dentition, high-frequency sugar consumption was associated with non-significant 15% higher odds of caries (OR 1.15, 95% CI 0.88 to 1.52), with no heterogeneity (I2=0%; ungraded).
1 finding from 1 review
Dental caries prevalence · Nigerian individuals, including children and adults, with primary or permanent dentition
High-frequency sugar consumption was associated with 18% higher but non-significant odds of dental caries in Nigeria (OR 1.18, 95% CI 0.87 to 1.59; I2=36%; ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
Permanent restoration after more than 14 days was associated with a pooled success rate of 23.2%.
1 finding from 1 review
At least 50% reduction in pain · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…
Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 4 hours (using pain intensity… compared with placebo; GRADE not reported.
3 findings from 1 review
RR 4.87 [2.83, 8.37]
17 studies · 1658 participants
GRADE not reported
RR 3.41 [2.34, 4.97]
13 studies · 1184 participants
GRADE not reported
RR 2.85 [1.89, 4.29]
16 studies · 1498 participants
GRADE not reported
Participant‐reported pain relief of 50% or greater · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…
Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 6 hours (using pain relief… compared with placebo; GRADE not reported.
1 finding from 1 review
Quality of root-end filling (retrograde/surgical treatment) · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment
The review found no eligible studies for this question.
1 finding from 1 review
Removal of broken (fractured) instruments from the root canal · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment
The review found no eligible studies for this question.
1 finding from 1 review
Total time required to complete the clinical procedure · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment
The review found no eligible studies for this question.
1 finding from 1 review
Repair of root perforations · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment
The review found no eligible studies for this question.
1 finding from 1 review
Quality of visualisation of root canal anatomy and morphology · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment
The review found no eligible studies for this question.
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Patients of any age who received endodontic therapy and were followed up for at least 1 year after treatment
The review found no eligible studies for this question.
1 finding from 1 review
Plaque index (PI) / oral hygiene · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)
School-based interventions may reduce dental plaque scores (SMD -0.32, favouring intervention), but the certainty of evidence is very low.
1 finding from 1 review
Oral hygiene measured by mean gingival scores · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)
The effect of school-based interventions on gingival scores is uncertain and not statistically significant (SMD 0.12; very low certainty).
1 finding from 1 review