Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 21 findings · 6 reviews · Heart · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 7 · 33.3%Low 8 · 38.1%Moderate 4 · 19%High 2 · 9.5%

Summary of findings table for the comparison of 'intensified patient care' vs usual care

Adherence to antipsychotic medication: number of missed doses, average endpoint data, short term (up to 6 months) · People receiving lipid‐lowering medications

Summary of findings table for the comparison of 'intensified patient… probably leads to higher medication adherence at ≤ 6 months compared with 'usual care' (moderate certainty).

1 finding from 1 review

Summary of findings table for the comparison of 'intensified patient care' vs usual care

Medication adherence (dichotomous) · People receiving lipid‐lowering medications

Summary of findings table for the comparison of 'intensified patient… leads to higher medication adherence at > 6 months compared with 'usual care' (high certainty).

1 finding from 1 review

Intervention not reported

New/intensified lipid‐lowering medication · adults without prevalent cardiovascular disease (primary cardiovascular disease prevention)

The intervention may leads to higher new/intensified lipid‐lowering medication (low certainty).

1 finding from 1 review

Intervention not reported

New/intensified antihypertensive medication · adults without prevalent cardiovascular disease (primary cardiovascular disease prevention)

The intervention may leads to higher new/intensified antihypertensive medication (low certainty).

1 finding from 1 review

Intervention not reported

Freedom from AF/AFL/AT off antiarrhythmic medications > 3 months · individuals with atrial fibrillation who are undergoing cardiac surgery

The intervention probably leads to higher freedom from AF/AFL/AT off antiarrhythmic medications > 3 months (moderate certainty).

1 finding from 1 review

Nurse‐led titration vs usual care

Proportion reaching target dose of medications · people with heart failure with reduced ejection fraction

Nurse‐led titration may leads to higher proportion reaching target dose of medications compared with usual care (low certainty).

1 finding from 1 review

Mobile phone text messages vs usual care

Fatal cardiovascular events (percentage of people having fatal cardiovascular events) · people with established arterial occlusive events

Mobile phone text messaging showed no clear difference in fatal cardiovascular events (percentage of people having fatal… compared with usual care (low certainty).

1 finding from 1 review