Annual increment in DMFS (D3) · Children and adolescents with permanent dentition
Not adjusted meta-regression beta was 0.43 per additional follow-up year.
5 findings from 1 review
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Not adjusted
Meta-regression beta per year of follow-up 0.43 [0.04, 0.83]
22 studies · 11300 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings and age at baseline
Meta-regression beta per year of follow-up 0.64 [0.31, 0.96]
22 studies · 11300 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings age at baseline and baseline caries experience
Meta-regression beta per year of follow-up 0.37 [0.04, 0.70]
22 studies · 11300 participants
GRADE not reported
Show 2 more findings
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-4 including relevance of evidence and risk of bias
Meta-regression beta per year of follow-up 0.46 [0.08, 0.83]
22 studies · 11300 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-3 including decade and preventive intervention
Meta-regression beta per year of follow-up 0.36 [-0.02, 0.73]
22 studies · 11300 participants
GRADE not reported
Annual increment in DMFT (D3) · Children and adolescents with permanent dentition
Not adjusted meta-regression beta was 0.18 per additional follow-up year.
5 findings from 1 review
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Not adjusted
Meta-regression beta per year of follow-up 0.18 [-0.04, 0.40]
13 studies · 24753 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings and age at baseline
Meta-regression beta per year of follow-up 0.18 [0.02, 0.35]
13 studies · 24753 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings age at baseline and baseline caries experience
Meta-regression beta per year of follow-up 0.23 [0.06, 0.40]
13 studies · 24753 participants
GRADE not reported
Show 2 more findings
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-4 including relevance of evidence and risk of bias
Meta-regression beta per year of follow-up -0.04 [-0.34, 0.26]
13 studies · 24753 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-3 including decade and preventive intervention
Meta-regression beta per year of follow-up 0.07 [-0.24, 0.39]
13 studies · 24753 participants
GRADE not reported
Caries incidence rate per person-year at risk (D3) · Children and adolescents with permanent dentition
Adjusted for groups 1-4 including relevance of evidence and risk of bias meta-regression beta was -0.02 per additional follow-up year.
5 findings from 1 review
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-4 including relevance of evidence and risk of bias
Meta-regression beta per year of follow-up -0.02 [-0.05, 0.01]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings age at baseline and baseline caries experience
Meta-regression beta per year of follow-up 0.00 [-0.00, 0.01]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for bitewings and age at baseline
Meta-regression beta per year of follow-up 0.00 [-0.00, 0.01]
15 studies · 10768 participants
GRADE not reported
Show 2 more findings
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Adjusted for groups 1-3 including decade and preventive intervention
Meta-regression beta per year of follow-up -0.00 [-0.02, 0.02]
15 studies · 10768 participants
GRADE not reported
Caries Progression Rates Revisited: A Systematic Review. 2019 All outcomesPer additional year of follow-up · Western or comparable populations · Not adjusted
Meta-regression beta per year of follow-up -0.00 [-0.01, 0.01]
15 studies · 10768 participants
GRADE not reported
Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth
codex
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
In the high-risk-study-excluded sensitivity meta-regression, longer follow-up was associated with lower success.
1 finding from 1 review
Severe pain for > 1 week · Patients with atrophic (resorbed) mandibles needing implants
Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to higher severe pain for > 1 week compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.
1 finding from 1 review
Experienced the operation negatively · Patients with atrophic (resorbed) mandibles needing implants
Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… showed no clear difference in experienced the operation negatively compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.
1 finding from 1 review
No improvement of facial appearance (3 weeks) · Patients with atrophic (resorbed) mandibles needing implants
Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to lower no improvement of facial appearance (3 weeks) compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.
1 finding from 1 review
Prosthetic failure (2 years) · Patients with atrophic (resorbed) mandibles needing implants
Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… showed no clear difference in prosthetic failure compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.
1 finding from 1 review
Major complications · Patients with atrophic (resorbed) mandibles needing implants
Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… led to higher major complications compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.
1 finding from 1 review
Implant failure · Patients with atrophic (resorbed) mandibles needing implants
Inlay/interposed bone graft (iliac or Bio-Oss block) + longer… showed no clear difference in implant failure compared with short implants (8 to 11 mm) without augmentation; GRADE not reported.
1 finding from 1 review
Interruptions to cancer treatment (radiotherapy breaks longer than two days) · Adults with cancer receiving treatment
Epidermal growth factor (EGF), oral spray showed no clear difference in interruptions to cancer treatment (radiotherapy breaks longer than… compared with placebo; GRADE not reported.
1 finding from 1 review
Healing - 1 year or longer · People requiring retreatment of periapical lesions (failed root canal therapy)
It is very uncertain whether intermediate restorative material (IRM) root-end filling changes healing - 1 year or longer compared with superEBA (very low certainty).
1 finding from 1 review
Healing - 1 year or longer · People requiring retreatment of periapical lesions (failed root canal therapy)
It is very uncertain whether intermediate restorative material (IRM) root-end filling changes healing - 1 year or longer compared with gutta-percha (very low certainty).
1 finding from 1 review
Quality of life · People aged 12 years and over with painful TMD lasting 3 months or longer
The review found no eligible studies for this question.
1 finding from 1 review
Reduction in pain intensity · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in pain intensity at treatment completion compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).
2 findings from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Relaxation showed no clear difference in pain intensity compared with occlusal (oral) appliance; GRADE not reported.
1 finding from 1 review
Psychological therapies for temporomandibular disorders (TMDs) 2022 · Cochrane All outcomesTreatment completion · Adolescents (12-19 years)
Not pooled. Wahlund 2015: MD 3.70 (95% CI -1.21 to 8.61), n=57 (relaxation 28, appliance 29); Wahlund 2003: MD not reported, n=83 (relaxation 41, appliance 42). Both studies were in adolescents; the occlusal appliance…
2 studies · 140 participants
GRADE not reported
Mental distress · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) may leads to lower psychological distress at follow-up compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).
2 findings from 1 review
Adverse events · People aged 12 years and over with painful TMD lasting 3 months or longer
1 finding from 1 review
Only 1 study reported adverse events as an outcome (Litt 2010): it found worsening symptoms in 13 people treated with an oral splint (as part of standard treatment) and 4 people treated with CBT.
1 study · 101 participants
Very low
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People aged 12 years and over with painful TMD lasting 3 months or longer
Hope-based intervention showed no clear difference in pain intensity compared with pain education; GRADE not reported.
1 finding from 1 review