Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 10 reviews

No studies found 1 · 4%GRADE not reported 5 · 20%Very low 14 · 56%Low 5 · 20%Moderate 0 · 0%High 0 · 0%

Induced hypertension vs placebo or no intervention

Proportion of participants with ≥ 1 serious adverse events · people with acute subarachnoid haemorrhage

It is very uncertain whether induced hypertension changes proportion of participants with ≥ 1 serious adverse events compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (maternal outcomes)

Hypertensive disorders of pregnancy · women with gestational diabetes mellitus

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with less‐tight glycaemic targets (maternal outcomes) (low certainty).

1 finding from 1 review

Probiotics vs placebo

Hypertensive disorders (including pre‐eclampsia, pregnancy‐induced hypertension, eclampsia) · women with gestational diabetes mellitus

Probiotic showed no clear difference in hypertensive disorders (including pre‐eclampsia, pregnancy‐induced… compared with placebo (low certainty).

1 finding from 1 review

Continuous glucose monitoring system vs intermittent glucose monitoring

Hypertensive disorders of pregnancy · women with pre‐existing diabetes

Continuous glucose monitoring may leads to lower hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with intermittent glucose monitoring (low certainty).

1 finding from 1 review

Self‐monitoring at home vs hospitalisation

Hypertensive disorders of pregnancy · women with pre‐existing diabetes

It is very uncertain whether self‐monitoring at home changes hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with hospitalisation (very low certainty).

1 finding from 1 review

Fetal biometry vs maternal glycaemic values

Hypertensive disorders of pregnancy · women with gestational diabetes mellitus and their babies

It is very uncertain whether fetal biometry changes hypertensive disorders of pregnancy (including pre‐eclampsia,… compared with maternal glycaemic values (very low certainty).

1 finding from 1 review

Dietary advice vs standard‐of‐care therapy

Hypertensive disorders of pregnancy (pregnancy‐induced hypertension) · pregnant women

Dietary advice interventions may leads to lower hypertensive disorders of pregnancy (pregnancy‐induced hypertension) compared with standard care (maternal outcomes) (low certainty).

1 finding from 1 review

Metformin vs insulin

Hypertensive disorders of pregnancy (pregnancy‐induced hypertension) · women with type 2 diabetes

Maternal outcomes: oral anti‐diabetic agent (metformin) may leads to lower hypertensive disorders of pregnancy: pregnancy‐induced hypertension compared with insulin (low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Hypertensive disorders of pregnancy (pregnancy‐induced hypertension) · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

It is very uncertain whether combined diet and exercise interventions changes hypertensive disorders of pregnancy (pregnancy‐induced… compared with standard care (mother) (very low certainty).

1 finding from 1 review