Findings

What do systematic reviews say?

114 questions · 127 findings · 8 reviews

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No studies found 13 · 10.2%GRADE not reported 0 · 0%Very low 35 · 27.6%Low 70 · 55.1%Moderate 9 · 7.1%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Double intrauterine insemination (IUI) vs single IUI · Clinical pregnancy ratea
  Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples 2021 · Cochrane Headline outcomes only
  OR 1.51 [1.23, 1.86]
  9 studies · 2716 participants
  Low
Direct match · question page
- Double intrauterine insemination (IUI) vs single IUI · Live birth ratea
  Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples 2021 · Cochrane Headline outcomes only
  OR 1.15 [0.71, 1.88]
  3 studies · 468 participants
  Low
Direct match · question page
- IUI vs FSP · Clinical pregnancy per couple
  Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility 2013 · Cochrane Headline outcomes only
  OR 0.75 [0.49, 1.12]
  14 studies · 1745 participants
  Low
Direct match · question page
- IUI vs FSP · Live birth per couple
  Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility 2013 · Cochrane Headline outcomes only
  OR 0.94 [0.59, 1.49]
  3 studies · 633 participants
  Low
Direct match · question page
- IUI vs FSP · Ectopic pregnancy per couple
  Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility 2013 · Cochrane Headline outcomes only
  OR 0.88 [0.24, 3.19]
  4 studies · 643 participants
  Very low

IUI vs FSP

Live birth rate per couple · women with non‐tubal infertility

IUI showed no clear difference in live birth per couple compared with FSP (low certainty).

1 finding from 1 review

Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility 2013 · Cochrane Headline outcomes only
OR 0.94 [0.59, 1.49]
3 studies · 633 participants
Low

IUI vs FSP

Clinical pregnancy rate · women with non‐tubal infertility

IUI showed no clear difference in clinical pregnancy per couple compared with FSP (low certainty).

1 finding from 1 review

Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility 2013 · Cochrane Headline outcomes only
OR 0.75 [0.49, 1.12]
14 studies · 1745 participants
Low

IUI vs FSP

Multiple pregnancy · women with non‐tubal infertility

IUI showed no clear difference in multiple pregnancy per couple compared with FSP (low certainty).

1 finding from 1 review

Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility 2013 · Cochrane Headline outcomes only
OR 0.62 [0.29, 1.32]
7 studies · 908 participants
Low

IUI vs FSP

Miscarriage per couple · women with non‐tubal infertility

IUI showed no clear difference in miscarriage per couple compared with FSP (low certainty).

1 finding from 1 review

Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility 2013 · Cochrane Headline outcomes only
OR 1.07 [0.56, 2.05]
7 studies · 884 participants
Low

IUI vs FSP

Ectopic pregnancy rate per couple · women with non‐tubal infertility

It is very uncertain whether IUI changes ectopic pregnancy per couple compared with FSP (very low certainty).

1 finding from 1 review

Intrauterine insemination versus fallopian tube sperm perfusion for non‐tubal infertility 2013 · Cochrane Headline outcomes only
OR 0.88 [0.24, 3.19]
4 studies · 643 participants
Very low

Double intrauterine insemination (IUI) vs single IUI

Live birth rate · stimulated cycles for subfertile couples

Double intrauterine insemination (IUI) showed no clear difference in live birth ratea compared with single IUI (low certainty).

1 finding from 1 review

Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples 2021 · Cochrane Headline outcomes only
OR 1.15 [0.71, 1.88]
3 studies · 468 participants
Low

Double intrauterine insemination (IUI) vs single IUI

Miscarriage · stimulated cycles for subfertile couples

Double intrauterine insemination (IUI) showed no clear difference in miscarriage ratea compared with single IUI (low certainty).

1 finding from 1 review

Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples 2021 · Cochrane Headline outcomes only
OR 1.78 [0.98, 3.24]
6 studies · 2363 participants
Low

Double intrauterine insemination (IUI) vs single IUI

Clinical pregnancy · stimulated cycles for subfertile couples

Double intrauterine insemination (IUI) may leads to higher clinical pregnancy ratea compared with single IUI (low certainty).

1 finding from 1 review

Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples 2021 · Cochrane Headline outcomes only
OR 1.51 [1.23, 1.86]
9 studies · 2716 participants
Low

Double intrauterine insemination (IUI) vs single IUI

Multiple pregnancy rate · stimulated cycles for subfertile couples

Double intrauterine insemination (IUI) showed no clear difference in multiple pregnancy ratea compared with single IUI (low certainty).

1 finding from 1 review

Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples 2021 · Cochrane Headline outcomes only
OR 2.04 [0.91, 4.56]
5 studies · 2203 participants
Low

Double intrauterine insemination (IUI) vs single IUI

Ectopic pregnancy · stimulated cycles for subfertile couples

Double intrauterine insemination (IUI) showed no clear difference in ectopic pregnancy ratea compared with single IUI (low certainty).

1 finding from 1 review

Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples 2021 · Cochrane Headline outcomes only
OR 1.22 [0.35, 4.28]
4 studies · 1048 participants
Low

IUI in a stimulated cycle vs IUI

Live birth rate per couple · couples with male subfertility

It is very uncertain whether IUI in stimulated cycles changes live birth rate per couple (all cycles) compared with IUI (very low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.34 [0.77, 2.33]
Studies not reported
Very low

IUI in a stimulated cycle vs IUI

OHSS · couples with male subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IUI in a stimulated cycle vs IUI

Pregnancy rate per couple (all cycles) · couples with male subfertility

It is very uncertain whether IUI in stimulated cycles changes pregnancy rate per couple (all cycles) compared with IUI (very low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.68 [1, 2.82]
Studies not reported
Very low

IUI in a stimulated cycle vs IUI

Miscarriage · couples with male subfertility

It is very uncertain whether IUI in stimulated cycles changes miscarriage rate per couple compared with IUI (very low certainty).

1 finding from 1 review

Assisted reproductive technologies for male subfertility 2016 · Cochrane Headline outcomes only
OR 1.06 [0.2, 5.63]
Studies not reported
Very low

IUI in a stimulated cycle vs IUI

Live birth rare per couple (all cycles) · participants with unexplained subfertility

IUI in a stimulated cycle may leads to higher live birth rare per couple (all cycles) compared with IUI (low certainty).

1 finding from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 2.07 [1.22, 3.5]
4 studies · 396 participants
Low

IUI in a stimulated cycle vs IUI

Multiple pregnancy rate · participants with unexplained subfertility

IUI in a stimulated cycle showed no clear difference in multiple pregnancy rate per couple compared with IUI (low certainty).

1 finding from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 3 [0.11, 78.27]
1 study · 39 participants
Low

IUI in a stimulated cycle vs IUI

Pregnancy rate per couple (all cycles) · participants with unexplained subfertility

IUI in a stimulated cycle showed no clear difference in pregnancy rate per couple (all cycles) compared with IUI (low certainty).

1 finding from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 6.43 [0.56, 73.35]
1 study · 26 participants
Low

IUI in a stimulated cycle vs IUI

Ovarian Hyperstimulation rate per woman ‐ not measured · participants with unexplained subfertility

The review found no eligible studies for this question.

1 finding from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

IUI in a stimulated cycle vs IUI

Miscarriage · participants with unexplained subfertility

IUI in a stimulated cycle showed no clear difference in miscarriage rate per couple compared with IUI (low certainty).

1 finding from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 5.21 [0.19, 141.08]
1 study · 26 participants
Low

IUI in a stimulated cycle vs IUI

Ectopic pregnancy rate per couple · participants with unexplained subfertility

It is very uncertain whether IUI in a stimulated cycle changes ectopic pregnancy rate per couple compared with IUI (very low certainty).

1 finding from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 6.48 [0.33, 127.09]
1 study · 211 participants
Very low