Cochrane · systematic review · CD003854
Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples
Rakic, L, Kostova, E, Cohlen, BJ, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library
Gynaecology and FertilityAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 100%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Double intrauterine insemination (IUI) compared to single IUI in stimulated cycles for subfertile couples
Population: stimulated cycles for subfertile couples
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Live birth ratea Double intrauterine insemination (IUI) vs single IUI | OR 1.15 [0.71, 1.88] | 3 studies · 468 participants | Low Downgraded: risk of bias, imprecision |
Miscarriage ratea Double intrauterine insemination (IUI) vs single IUI | OR 1.78 [0.98, 3.24] | 6 studies · 2363 participants | Low Downgraded: risk of bias, imprecision |
Clinical pregnancy ratea Double intrauterine insemination (IUI) vs single IUI | OR 1.51 [1.23, 1.86] | 9 studies · 2716 participants | Low Downgraded: risk of bias, imprecision, indirectness |
Multiple pregnancy ratea Double intrauterine insemination (IUI) vs single IUI | OR 2.04 [0.91, 4.56] | 5 studies · 2203 participants | Low Downgraded: risk of bias, imprecision |
Ectopic pregnancy ratea Double intrauterine insemination (IUI) vs single IUI | OR 1.22 [0.35, 4.28] | 4 studies · 1048 participants | Low Downgraded: risk of bias, imprecision |