Findings

What do systematic reviews say?

16 questions · 16 findings · 4 reviews

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No studies found 5 · 31.3%GRADE not reported 2 · 12.5%Very low 1 · 6.3%Low 8 · 50%Moderate 0 · 0%High 0 · 0%

Hypnotics vs inactive control

cAHI · adults with primary central sleep apnoea

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 5 participants
GRADE not reported

Hypnotics vs inactive control

Cardiovascular mortality · adults with primary central sleep apnoea

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hypnotics vs inactive control

Serious adverse events · adults with primary central sleep apnoea

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hypnotics vs inactive control

Quality of sleep · adults with primary central sleep apnoea

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hypnotics vs inactive control

Quality of lifeÂ · adults with primary central sleep apnoea

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hypnotics vs inactive control

AHI · adults with primary central sleep apnoea

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 5 participants
GRADE not reported

Hypnotics vs inactive control

All‐cause mortality · adults with primary central sleep apnoea

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological treatment for central sleep apnoea in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Zuclopenthixol dihydrochloride vs sulpiride

Adverse effects: Clinically important general adverse effect ‐ requiring hypnotics/sedatives · schizophrenia

It is very uncertain whether zuclopenthixol dihydrochloride changes adverse effects: Clinically important general adverse effect ‐… compared with sulpiride (very low certainty).

1 finding from 1 review

Zuclopenthixol dihydrochloride for schizophrenia 2017 · Cochrane Headline outcomes only
RR 0.6 [0.27, 1.32]
1 study · 61 participants
Very low

Intervention not reported

Apnoea‐ hypopnoea index (AHI) (events/h) · participants with sleep apnoea prescribed sedatives, hypnotics (including benzodiazepines (BZDs), non‐BZD GABAA receptor agonists ('Z…

1 finding from 1 review

Effects of opioid, hypnotic and sedating medications on sleep‐disordered breathing in adults with obstructive sleep… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Oxygen desaturation index (ODI) · participants with sleep apnoea prescribed sedatives, hypnotics (including benzodiazepines (BZDs), non‐BZD GABAA receptor agonists ('Z…

1 finding from 1 review

Effects of opioid, hypnotic and sedating medications on sleep‐disordered breathing in adults with obstructive sleep… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intervention not reported

Fall in minimum SpO2 · participants with sleep apnoea prescribed sedatives, hypnotics (including benzodiazepines (BZDs), non‐BZD GABAA receptor agonists ('Z…

1 finding from 1 review

Effects of opioid, hypnotic and sedating medications on sleep‐disordered breathing in adults with obstructive sleep… 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Methohexital vs propofol

Change in Hamilton Depression Scale scores Scale of Hamilton Depression scores · patients with depressive patients receiving MECT

1 finding from 1 review

Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with… 2014 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 165 participants
Low

Methohexital vs propofol

EEG seizure duration EEG detection and measurement · patients with depressive patients receiving MECT

1 finding from 1 review

Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 119 participants
Low

Methohexital vs propofol

Motor seizure duration Direct observation of motor seizure · patients with depressive patients receiving MECT

1 finding from 1 review

Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 78 participants
Low

Thiopental vs propofol

Mean EEG seizure duration · patients with major depression treated with ECT

1 finding from 1 review

Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 90 participants
Low

Thiopental vs propofol

Mean time to recovery Time to follow commands · patients with major depression treated with ECT

1 finding from 1 review

Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 48 participants
Low