evidence/gaps
Cochrane · systematic review · CD009763

Different regimens of intravenous sedatives or hypnotics for electroconvulsive therapy (ECT) in adult patients with depression

Peng, L, Min, S, Wei, K, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 5 · 100%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Methohexital compared with propofol for depressive patients receiving MECT

Population: patients with depressive patients receiving MECT
3 questions
OutcomeEffectEvidenceStatus / GRADE
Change in Hamilton Depression Scale scores Scale of Hamilton Depression scores
Methohexital vs propofol
no estimate extracted4 studies · 165 participantsLow
EEG seizure duration EEG detection and measurement
Methohexital vs propofol
no estimate extracted2 studies · 119 participantsLow
Downgraded: imprecision
Motor seizure duration Direct observation of motor seizure
Methohexital vs propofol
no estimate extracted2 studies · 78 participantsLow
Downgraded: imprecision

Thiopental compared with propofol for patients receiving ECT

Population: patients with major depression treated with ECT
2 questions
OutcomeEffectEvidenceStatus / GRADE
Mean EEG seizure duration
Thiopental vs propofol
no estimate extracted2 studies · 90 participantsLow
Downgraded: risk of bias
Mean time to recovery Time to follow commands
Thiopental vs propofol
no estimate extracted2 studies · 48 participantsLow
Downgraded: risk of bias, inconsistency