Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 40 findings · 8 reviews · Dental caries

No studies found 8 · 20%GRADE not reported 17 · 42.5%Very low 4 · 10%Low 10 · 25%Moderate 1 · 2.5%High 0 · 0%

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Restoration failure (permanent, mature dentition; root surfaces) · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

It is very uncertain whether ART using resin-modified glass ionomer cement (RM-GIC) changes restoration failure (permanent, mature dentition; root surfaces) compared with conventional treatment using RM-GIC (very low certainty).

1 finding from 1 review

Light-cured resin-modified glass ionomer cement vs Glass ionomer cement (GIC)

Secondary caries · Patients requiring dental restoration; permanent teeth

Over 1 year in permanent teeth, secondary caries did not differ significantly between RMGIC and GIC (RR 1.82, 95% CI 0.45-7.28; low certainty).

2 findings from 1 review

High-viscosity glass-ionomer ART restorations vs Conventional treatment using H-GIC (rotary instruments)

Restoration failure (permanent dentition) · People with dental caries in primary teeth (mainly children)

The review found no eligible studies for this question.

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Restoration failure (permanent, immature teeth) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)

ART using glass ionomer cement (GIC) led to higher restoration failure (permanent, immature teeth) compared with conventional treatment using amalgam; GRADE not reported.

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Pain (permanent, immature teeth) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)

ART using glass ionomer cement (GIC) led to lower pain (permanent, immature teeth) compared with conventional treatment using amalgam; GRADE not reported.

1 finding from 1 review

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Secondary caries · Older adults with root caries in permanent (mature) teeth (mean age 75 years)
1 finding from 1 review

ART using resin-modified glass ionomer cement (RM-GIC) vs Conventional treatment using RM-GIC

Restoration failure (primary dentition) · Older adults with root caries in permanent (mature) teeth (mean age 75 years)

The review found no eligible studies for this question.

1 finding from 1 review

ART sealant using high-viscosity glass ionomer (press-finger technique) vs Resin-based sealant

Development of carious lesions on sealed occlusal pits and fissures · Children with fully erupted permanent first molar teeth (mean age about 6 to 8 years)

At 48 months, no statistically significant difference was found between HVGIC and resin-based sealants (RR 0.62, 95% CI 0.31 to 1.21); evidence ungraded and at high risk of bias.

4 findings from 1 review
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A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique

Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of anterior teeth, irrespective of…

The review found no eligible studies for this question.

1 finding from 1 review

A permanent restorative material or technique (e.g. amalgam; glass ionomer (type I-IV); composite resin (macrofilled, microfilled, hybrid, nanofilled); resin-modified glass ionomer (compomer, giomer); cement/cermet; stainless steel or nickel-chrome crown; pre-fabricated resin/porcelain veneer facing; microabrasion) vs A different permanent restorative material or technique

Outcome not reported · Children and adolescents under 18 years with amelogenesis imperfecta requiring restorative care of posterior teeth, irrespective of…

The review found no eligible studies for this question.

1 finding from 1 review

Glass ionomer cement vs Resin composite restoration

Secondary caries · Patients requiring dental restoration; permanent teeth

Over 2 or more years in permanent teeth, GIC probably reduces secondary caries versus resin composite (RR 0.50, 95% CI 0.28-0.91; moderate certainty).

2 findings from 1 review

38% silver diamine fluoride vs Glass ionomer cement (GIC) plus fluoride varnish

Caries prevention (preventive fraction, SDF vs GIC+5% fluoride varnish) · intellectually disabled individuals with caries in permanent posterior teeth

SDF had a 45% preventative fraction versus glass ionomer cement plus fluoride varnish; no pooled estimate or GRADE rating was reported.

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Restoration failure (primary dentition) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)

ART using glass ionomer cement (GIC) showed no clear difference in restoration failure (primary teeth) compared with conventional treatment using amalgam; GRADE not reported.

1 finding from 1 review

ART using glass ionomer cement (GIC) vs Amalgam restoration

Participant experience (co-operation during procedure) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)
1 finding from 1 review

Glass ionomer-based sealant vs Resin-based sealant

Caries occurrence on sealed teeth · Sealed permanent teeth

Glass-ionomer and resin-based fissure sealants showed no statistically significant difference in caries occurrence on sealed permanent teeth at 12 months (no GRADE rating).

3 findings from 1 review