Non-Cochrane · intervention · PM24212996
The modified Ottawa method to establish the update need of a systematic review: glass-ionomer versus resin sealants for caries prevention.
Mickenautsch Steffen, Yengopal Veerasamy · Journal of applied oral science : revista FOB · 2013 · PubMed · doi:10.1590/1679-775720130014
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
6
current version
GRADE rated
0
No studies
0
Included studies
4
linked below
No studies 0 · 0%Ungraded 6 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Teeth with pits and fissures sealed with either GIC or resin | Sealed permanent teeth |
| Intervention | Conventional glass-ionomer cement (GIC) fissure sealants | Conventional glass-ionomer cement (GIC) fissure sealants |
| Comparison | Resin-based fissure sealants | Resin-based fissure sealants |
| Outcomes | Caries occurrence on sealed pits and fissures | Caries occurrence on sealed teeth (n/N) |
| Study designs | Systematic reviews and/or prospective clinical control trials | Clinical trial reports (n=4) |
| Timing | Not specified | 6 months; 12 months; 24 months |
Search date: 26 April 2012. Databases: Expanded Academic ASAP PLUS; BMC; Cochrane Oral Health Reviews; DOAJ; Meta Register of Controlled Trials; ScienceDirect; PubMed; reference check; ad hoc hand search
Questions and results
Conventional glass-ionomer cement (GIC) fissure sealants vs Resin-based fissure sealants
Population: Sealed permanent teeth
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Caries occurrence on sealed teeth 6 months · 6 months (permanent teeth) Glass-ionomer and resin-based fissure sealants showed no statistically significant difference in caries occurrence on sealed permanent teeth at 6 months (no GRADE rating). Source: Figure 4 (forest plot); Results, Data analysis and signal identification · same question in other reviews | RR 2.04 [0.62, 6.70] | 6 studies · 1944 participants | Ungraded |
Caries occurrence on sealed teeth 24 months · 24 months (permanent teeth) Glass-ionomer and resin-based fissure sealants showed no statistically significant difference in caries occurrence on sealed permanent teeth at 24 months (no GRADE rating). Source: Figure 6 (forest plot); Results, Data analysis and signal identification · same question in other reviews | RR 1.51 [1.00, 2.28] | 8 studies · 2810 participants | Ungraded |
Caries occurrence on sealed teeth 12 months · 12 months (permanent teeth) Glass-ionomer and resin-based fissure sealants showed no statistically significant difference in caries occurrence on sealed permanent teeth at 12 months (no GRADE rating). Source: Figure 5 (forest plot); Results, Data analysis and signal identification · same question in other reviews | RR 1.66 [0.75, 3.68] | 5 studies · 1952 participants | Ungraded |
Comparison
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Caries occurrence on sealed teeth 24 months, original datasets only (permanent teeth) | RR 2.10 [1.23, 3.58] | 4 studies | Ungraded |
Caries occurrence on sealed teeth 12 months, original datasets only (permanent teeth) | RR 2.61 [0.61, 11.14] | 2 studies | Ungraded |
Caries occurrence on sealed teeth 6 months, original datasets only (permanent teeth) | RR 1.81 [0.39, 8.37] | 3 studies | Ungraded |
AMSTAR 2 appraisal
Two independent extractors rated each item. Their ratings are shown side by side because they have not been reconciled yet. The overall rating follows Shea et al. 2017: one critical flaw gives Low, more than one gives Critically Low.
| Item | Extractor A | Extractor B | Agree |
|---|---|---|---|
| 1Research question includes PICO components | Yes | Yes | yes |
| 2Protocol established before the reviewcritical | No | No | yes |
| 3Choice of study designs explained | No | No | yes |
| 4Comprehensive literature searchcritical | Partial Yes | Partial Yes | yes |
| 5Study selection in duplicate | Yes | Yes | yes |
| 6Data extraction in duplicate | Yes | Yes | yes |
| 7List of excluded studies with reasonscritical | No | No | yes |
| 8Included studies described in detail | No | No | yes |
| 9Risk of bias assessed satisfactorilycritical | RCT: No · NRSI: No | NRSI: No · RCT: No | no |
| 10Funding of included studies reported | No | No | yes |
| 11Appropriate meta-analysis methodscritical | RCT: No · NRSI: No | NRSI: No · RCT: No | no |
| 12Impact of risk of bias on the pooled results | No | No | yes |
| 13Risk of bias accounted for in interpretationcritical | No | No | yes |
| 14Heterogeneity explained | No | No | yes |
| 15Publication bias investigatedcritical | No | No | yes |
| 16Conflicts of interest reported | Yes | No | no |
| Overall | Critically Low | Critically Low | yes |
Included primary studies 4
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| Chen 2012 Caries-preventive effect of sealants produced with altered glass-ionomer materials, after 2 years. PMID:22300651 | 1 other review | not stated | not extracted yet | not extracted yet |
| Antonson 2012 Twenty-four month clinical evaluation of fissure sealants on partially erupted permanent first molars: glass ionomer versus resin-based… PMID:22298552 | this review only | not stated | not extracted yet | not extracted yet |
| Dhar 2012 Evaluation of resin based and glass ionomer based sealants placed with or without tooth preparation-a two year clinical trial. PMID:22353457 | this review only | not stated | not extracted yet | not extracted yet |
| Ulusu 2012 The success rates of a glass ionomer cement and a resin-based fissure sealant placed by fifth-year undergraduate dental students. PMID:22449810 | this review only | not stated | not extracted yet | not extracted yet |
Overlap with other reviews
Reviews that include the same primary studies are not independent evidence. Shared counts match studies by PMID, DOI or NCT, and otherwise by author and year (a probable match).
| Review | Shared studies | Jaccard |
|---|---|---|
| Caries-Preventive Effect of High-Viscosity Glass Ionomer and Resin-Based Fissure Sealants on Permanent Teeth: A Systematic Review of… (2016) | 1 | 0.10 |