Pain ‐ fentanyl · adults and children undergoing general anaesthesia including the muscle relaxant rocuronium bromide
Fentanyl may leads to lower pain ‐ fentanyl compared with placebo (low certainty).
1 finding from 1 review
Emergence agitation—Fentanyl · patients with emergence agitation
Other GA/adjunct leads to lower emergence agitation—Fentanyl compared with sevoflurane anaesthesia (high certainty).
1 finding from 1 review
Number requiring opioids postoperatively · patients with postoperative pain
Clonidine showed no clear difference in number requiring opioids postoperatively compared with fentanyl (moderate certainty).
1 finding from 1 review
Single small study · patients with postoperative pain
1 finding from 1 review
no estimate extracted
1 participants
GRADE not reported
Additional analgesia required (escape analgesia) · patients with postoperative pain
Clonidine showed no clear difference in number requiring additional analgesia at any time postoperatively compared with fentanyl (moderate certainty).
1 finding from 1 review
Intervention not reported
Pain reduction (mean VAS) Pain assessed before analgesia (0 min) and at 5, 10, 20 and 30 min after analgesia · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Respiratory depression · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Hypotension · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Decreased level of consciousness · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Intolerance to analgesia · children (aged < 18 years) with acute severe pain
1 finding from 1 review
Intervention not reported
Use of ED "rescue" analgesia · children (aged < 18 years) with acute severe pain
1 finding from 1 review