Combined oral and intravenous leads to lower surgical wound infection: oral + iv versus iv alone compared with oral or intravenous alone (high certainty).
It is very uncertain whether summary of findings table ‐ Combined mechanical and oral antibiotic… changes surgical site infections compared with oral antibiotics alone (very low certainty).
Preoperative radiotherapy showed no clear difference in overall mortality ‐ only total mesorectal excision ( compared with surgery alone (low certainty).
Preoperative radiotherapy showed no clear difference in curative resection ( compared with surgery alone (low certainty).
The review found no eligible studies for this question.
Enema plus dexamethasone showed no clear difference in bowel resection compared with enema alone (low certainty).
Summary of findings table ‐ Combined mechanical and oral antibiotic… probably leads to lower SSI compared with mechanical bowel preparation alone (moderate certainty).
Summary of findings table ‐ Combined mechanical and oral antibiotic… probably leads to lower anastomotic leakage compared with mechanical bowel preparation alone (moderate certainty).
Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in mortality compared with mechanical bowel preparation alone (moderate certainty).
Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in incidence of postoperative ileus compared with mechanical bowel preparation alone (low certainty).
Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in anastomotic leakage compared with oral antibiotics alone (low certainty).
Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in mortality compared with oral antibiotics alone (low certainty).
Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in incidence of postoperative ileus compared with oral antibiotics alone (low certainty).
Preoperative radiotherapy probably leads to lower overall mortality ( compared with surgery alone (moderate certainty).
Preoperative radiotherapy showed no clear difference in cause‐specific mortality ( compared with surgery alone (low certainty).
Preoperative radiotherapy probably leads to lower local recurrence ( compared with surgery alone (moderate certainty).
Preoperative radiotherapy showed no clear difference in sphincter preservation ( compared with surgery alone (low certainty).
Preoperative radiotherapy may leads to higher postoperative morbidity ‐ sepsis (within 30 days after surgery) compared with surgery alone (low certainty).