Acute postoperative pain 0 to 6 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
Acute postoperative pain at 12 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
Acute postoperative pain at 24 hours (Score 0 to 10, VAS or NRS Scale) · adults undergoing brain surgery
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing brain surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Analgesia requirements · adults undergoing brain surgery
1 finding from 1 review
Analgesic Success · adults undergoing brain surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects: 1. Sedation · adults undergoing brain surgery
1 finding from 1 review
Chronic Headache · adults undergoing brain surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · adults undergoing brain surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery
Dexmedetomidine showed no clear difference in adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo medications (low certainty).
1 finding from 1 review
Hypotension · adults undergoing brain surgery
Dexmedetomidine may leads to lower adverse event hypotension (0 to 24 hours) compared with control or placebo medications (low certainty).
1 finding from 1 review
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
1 finding from 1 review
Duration of mechanical ventilation · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
Risk of delirium · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes risk of delirium compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Risk of coma · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes risk of coma compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Bradycardia · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes incidence of bradycardia compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Total duration of weaning defined as study randomization to successful extubation (hours) · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
Duration of ICU stay · Critically ill patients requiring long‐term sedation during mechanical ventilation
1 finding from 1 review
All‐cause mortality · Critically ill patients requiring long‐term sedation during mechanical ventilation
It is very uncertain whether dexmedetomidine changes mortality compared with traditional sedative agents (very low certainty).
1 finding from 1 review
Emergence agitation—Dexmedetomidine · patients with emergence agitation
Other GA/adjunct leads to lower emergence agitation—Dexmedetomidine compared with sevoflurane anaesthesia (high certainty).
1 finding from 1 review