Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

77 questions · 78 findings · 15 reviews

No studies found 8 · 10.3%GRADE not reported 7 · 9%Very low 22 · 28.2%Low 26 · 33.3%Moderate 11 · 14.1%High 4 · 5.1%

Continuous support vs usual care

Negative rating of/negative feelings about birth experience · women during childbirth

Continuous support may leads to lower negative rating of/negative feelings about birth experience compared with usual care (all trials) (low certainty).

1 finding from 1 review

Continuous support vs usual care

Neonatal admission to special care · women during childbirth

Continuous support showed no clear difference in admission to special care nursery compared with usual care (all trials) (low certainty).

1 finding from 1 review

Continuous support vs usual care

Exclusive or any breastfeeding at any time point, as defined by trial authors · women during childbirth

Continuous support showed no clear difference in exclusive or any breastfeeding at any time point, as defined by… compared with usual care (all trials) (low certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care

Cardiovascular mortality

Continuous positive airway pressure (CPAP) plus best supportive care showed no clear difference in cardiovascular mortality ‐ after 24 months Number of participants:… compared with best supportive care (low certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care

All‐cause mortality ‐ after 24 months Number of participants: 287(2 RCTs)

It is very uncertain whether continuous positive airway pressure (CPAP) plus best supportive care changes all‐cause mortality ‐ after 24 months Number of participants: 287(2… compared with best supportive care (very low certainty).

1 finding from 1 review

Continuous positive airway pressure (CPAP) plus best supportive care vs best supportive care

Time to life‐saving cardiovascular intervention

Continuous positive airway pressure (CPAP) plus best supportive care may leads to lower time to life‐saving cardiovascular intervention ( compared with best supportive care (low certainty).

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

Death (before hospital discharge) or BPD (supplemental oxygen/respiratory support at 36 weeks' postmenstrual age if born < 32 weeks' gestation, or 28 days if born ≥ 32 weeks' gestation) · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in death (before hospital discharge) or BPD(supplemental… compared with continuous positive airway pressure (low certainty).

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

BPD (supplemental oxygen/respiratory support at 36 weeks' postmenstrual age if born < 32 weeks' gestation, or 28 days if born ≥ 32 weeks' gestation) · preterm infants requiring primary respiratory support

Nasal high flow showed no clear difference in BPD (supplemental oxygen/respiratory support at 36 weeks'… compared with continuous positive airway pressure (low certainty).

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

Duration of any form of respiratory support (any form of non‐invasive respiratory support with or without supplemental oxygen) · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
1 finding from 1 review