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Evidence found and GRADE certainty

182 questions · 183 findings · 20 reviews · Headline outcomes only

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No studies found 46 · 25.1%GRADE not reported 5 · 2.7%Very low 51 · 27.9%Low 37 · 20.2%Moderate 34 · 18.6%High 10 · 5.5%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Summary of findings table ‐ Prothrombin complex concentrates vs any comparator

Mortality within the longest · patients with vitamin K antagonist‐induced bleeding requiring acute intervention

It is very uncertain whether prothrombin complex concentrate changes overall mortality ‐ longest compared with any comparator (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Prothrombin complex concentrates vs any comparator

Number of new occurrences of RBC transfusion · patients with vitamin K antagonist‐induced bleeding requiring acute intervention

It is very uncertain whether prothrombin complex concentrate changes number of new occurrences of RBC transfusion compared with any comparator (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Prothrombin complex concentrates vs any comparator

Number of complications probably related to the intervention · patients with vitamin K antagonist‐induced bleeding requiring acute intervention

It is very uncertain whether prothrombin complex concentrate changes number of complications probably related to the intervention compared with any comparator (very low certainty).

1 finding from 1 review

Information or education intervention as part of a complex intervention vs complex intervention without information or education

Patient or carer satisfaction with information provided CCFNI (between day 3 and day 5); scale from 14 to 56 Lower scores indicate increased satisfaction. FS‐ICU 24 (90 days after randomisation); scale from 0 to 100 Lower scores indicate less sati... · adult ICU patients and their carers
1 finding from 1 review

Multivitamin vs control

Cognitive function · cognitively healthy people in mid and late life
2 findings from 1 review

Complex information, support and training interventions vs information only

Leaving the study early · Informal caregivers of people with dementia

Complex information, support and training interventions probably leads to higher dropouts for any reason compared with information provision only (moderate certainty).

1 finding from 1 review

Complex information, support and training interventions vs information only

Institutional care ‐ nursing home placement · Informal caregivers of people with dementia

It is very uncertain whether complex information, support and training interventions changes institutional care ‐ nursing home placement compared with information provision only (very low certainty).

1 finding from 1 review