Cochrane · systematic review · CD011895

Improving vaccination uptake among adolescents

Abdullahi, LH, Kagina, BM, Ndze, VN, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
14
current version
GRADE rated
14
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 7.1%Low 4 · 28.6%Moderate 8 · 57.1%High 1 · 7.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Health education compared to usual practice

Population: adolescents and parents
1 question
OutcomeEffectEvidenceStatus / GRADE
Uptake of HPV vaccinea
Health education vs usual practice
no estimate extracted3 studies · 1054 participantsHigh

Complex compared to simplified health education

Population: adolescents
1 question
OutcomeEffectEvidenceStatus / GRADE
Uptake of hepatitis B vaccineb
Complex vs simplified health education
no estimate extracted1 study · 17411 participantsModerate
Downgraded: risk of bias

Financial incentives compared to usual practice

Population: adolescents
1 question
OutcomeEffectEvidenceStatus / GRADE
Uptake of HPV vaccineb
Financial incentives vs usual practice
no estimate extracted1 study · 500 participantsLow
Downgraded: risk of bias, imprecision

Health education plus financial incentives compared to usual practice

Population: adolescents and parents
1 question
OutcomeEffectEvidenceStatus / GRADE
Uptake of hepatitis B vaccineb
Health education plus financial incentives vs usual practice
no estimate extracted1 study · 104 participantsVery low
Downgraded: risk of bias, imprecision, indirectness

Mandatory vaccination versus usual practice

Population: adolescents
1 question
OutcomeEffectEvidenceStatus / GRADE
Uptake of hepatitis B vaccinea
Mandatory vaccination vs usual practice
no estimate extracted1 study · 2642 participantsModerate

Provider prompts compared to usual practice

Population: healthcare workers
4 questions
OutcomeEffectEvidenceStatus / GRADE
Uptake of HPV vaccineb
Provider prompts vs usual practice
no estimate extracted2 studies · 859 participantsModerate
Downgraded: imprecision
Uptake of Tdap vaccineb
Provider prompts vs usual practice
no estimate extracted2 studies · 3296 participantsModerate
Downgraded: imprecision
Uptake of meningococcal conjugate vaccineb
Provider prompts vs usual practice
no estimate extracted2 studies · 3219 participantsModerate
Downgraded: imprecision
Uptake of seasonal influenza vaccineb
Provider prompts vs usual practice
no estimate extracted2 studies · 1439 participantsModerate
Downgraded: imprecision

Provider education with performance feedback compared to usual practice

Population: paediatricians and nurse practitioners
1 question
OutcomeEffectEvidenceStatus / GRADE
Uptake of HPV vaccinationa
Provider education with performance feedback vs usual practice
no estimate extracted2e+05 participantsLow

Class‐based compared to age‐based HPV vaccination in schools

Population: adolescents
1 question
OutcomeEffectEvidenceStatus / GRADE
HPV vaccine uptakea
Class‐based vs age‐based HPV vaccination
no estimate extracted1 study · 5537 participantsModerate
Downgraded: imprecision, indirectness

Multi‐component provider intervention compared to usual practice

Population: healthcare providers and their adolescent patients (boys and girls aged 11–21 years)
1 question
OutcomeEffectEvidenceStatus / GRADE
HPV vaccine uptakeb
Multi‐component provider intervention vs usual practice
no estimate extracted1 study · 15849 participantsModerate
Downgraded: imprecision, indirectness

Multi‐component provider and parent intervention compared to usual practice

Population: healthcare workers and parents
2 questions
OutcomeEffectEvidenceStatus / GRADE
HPV vaccine uptake at 3 months
Multi‐component provider and parent intervention vs usual practice
no estimate extracted1 study · 337 participantsLow
Downgraded: risk of bias, imprecision
HPV vaccine uptake at 6 months
Multi‐component provider and parent intervention vs usual practice
no estimate extracted1 study · 25869 participantsLow
Downgraded: risk of bias, imprecision