All‐cause mortality · Kaposi sarcoma in children with HIV‐1 infection
It is very uncertain whether combination Chemotherapy + ART changes mortality compared with single Agent Chemotherapy + ART (very low certainty).
1 finding from 1 review
RR 0.38 [0.24, 0.58]
50 participants
Very low
All‐cause mortality · patients with initial treatment of HIV infection in antiretroviral‐naive individuals
It is very uncertain whether d4T changes mortality compared with AZT (very low certainty).
1 finding from 1 review
Clinical progression · patients with initial treatment of HIV infection in antiretroviral‐naive individuals
d4T showed no clear difference in clinical progression compared with AZT (low certainty).
1 finding from 1 review
Severe adverse events · patients with initial treatment of HIV infection in antiretroviral‐naive individuals
d4T showed no clear difference in severe adverse events compared with AZT (low certainty).
1 finding from 1 review
Virologic response · patients with initial treatment of HIV infection in antiretroviral‐naive individuals
d4T showed no clear difference in virologic response compared with AZT (low certainty).
1 finding from 1 review
Adherence/tolerability/retention · patients with initial treatment of HIV infection in antiretroviral‐naive individuals
d4T showed no clear difference in adherence/tolerability/retention compared with AZT (low certainty).
1 finding from 1 review
Immunologic response · patients with initial treatment of HIV infection in antiretroviral‐naive individuals
1 finding from 1 review
Drug resistance · patients with initial treatment of HIV infection in antiretroviral‐naive individuals
It is very uncertain whether d4T changes drug resistance compared with AZT (very low certainty).
1 finding from 1 review
Serious adverse events · patients with initial ART
TDF showed no clear difference in serious adverse events compared with AZT (high certainty).
1 finding from 1 review
Virologic response · patients with initial ART
TDF showed no clear difference in virologic response compared with AZT (high certainty).
1 finding from 1 review
Adherence/tolerability/retention · patients with initial ART
TDF probably leads to higher adherence/tolerability/retention compared with AZT (moderate certainty).
1 finding from 1 review
Immunological response · patients with initial ART
1 finding from 1 review
Drug resistance · patients with initial ART
It is very uncertain whether TDF changes drug resistance compared with AZT (very low certainty).
1 finding from 1 review