Clinical failure · adults and children with enteric fever
Cefixime may leads to higher clinical failure compared with fluoroquinolones (low certainty).
1 finding from 1 review
Microbiological failure · adults and children with enteric fever
Cefixime showed no clear difference in microbiological failure compared with fluoroquinolones (low certainty).
1 finding from 1 review
Relapse · adults and children with enteric fever
Cefixime may leads to higher relapse compared with fluoroquinolones (low certainty).
1 finding from 1 review
Time to defervescence · adults and children with enteric fever
Cefixime may leads to higher time to defervescence compared with fluoroquinolones (low certainty).
1 finding from 1 review
Length of hospital stay · adults and children with enteric fever
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Convalescent faecal carriage · adults and children with enteric fever
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events · adults and children with enteric fever
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical attachment level (CAL) · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in clinical attachment level (CAL) compared with SRP; GRADE not reported.
1 finding from 1 review
Adverse events · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in adverse events compared with SRP; GRADE not reported.
1 finding from 1 review
The only included trial (Dukic 2016) reported nausea, dizziness and/or anorexia in the cefixime + SRP group.
1 study · 60 participants
GRADE not reported
Percentage of bleeding on probing (BOP) · Adults with chronic periodontitis
Cefixime + SRP led to lower percentage of bleeding on probing (BOP) compared with SRP; GRADE not reported.
1 finding from 1 review
Probing pocket depth · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in probing pocket depth compared with SRP; GRADE not reported.
1 finding from 1 review
Intervention not reported
Cefixime (1 RCT; 38 participants) · people with cirrhosis and spontaneous bacterial peritonitis
It is very uncertain whether the intervention changes cefixime (1 RCT; 38 participants) (very low certainty).
1 finding from 1 review
HR 1.26 [0.26, 6.9]
Studies not reported
Very low
Adverse events including treatment‐related adverse events · pregnant women with gonorrhoea infection
1 finding from 1 review
Cure of gonococcal infection (microbiological culture) · pregnant women with gonorrhoea infection
It is very uncertain whether intramuscular ceftriaxone changes cure of gonococcal infection (microbiological culture) compared with oral cefixime (very low certainty).
1 finding from 1 review
Incidence of obstetric complications · pregnant women with gonorrhoea infection
1 finding from 1 review
Incidence of disseminated gonococcal infection · pregnant women with gonorrhoea infection
1 finding from 1 review
Neonatorum ophthalmia · pregnant women with gonorrhoea infection
1 finding from 1 review