Cefixime vs fluoroquinolones: Microbiological failure
Cefixime showed no clear difference in microbiological failure compared with fluoroquinolones (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Cefixime vs fluoroquinolones Microbiological failure · adults and children with enteric fever Cefixime showed no clear difference in microbiological failure compared with fluoroquinolones (low certainty). Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins (2022) · Cochrane Headline outcomes only | RR 4.07 [0.46, 36.41] | 2 studies · 240 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.