Cochrane · systematic review · CD013120
Antibiotic treatment for spontaneous bacterial peritonitis in people with decompensated liver cirrhosis: a network meta‐analysis
Iogna Prat, L, Wilson, P, Freeman, SC, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
Hepato-BiliaryAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
11
current version
GRADE rated
9
No studies
2
Included studies
NR
No studies 2 · 18.2%Ungraded 0 · 0%Very low 9 · 81.8%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: people with cirrhosis and spontaneous bacterial peritonitis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Interventions | no estimate extracted | NR | No studies |
Cefotaxime (1 RCT; 37 participants) | HR 0.56 [0.11, 2.28] | NR | Very low Downgraded: risk of bias, imprecision |
Ciprofloxacin (1 RCT; 35 participants) | HR 0.65 [0.12, 2.72] | NR | Very low Downgraded: risk of bias, imprecision |
Ceftazidime (No direct RCT) | HR 1.15 [0.17, 6.37] | NR | Very low Downgraded: risk of bias, imprecision |
Amikacin (No direct RCT) | HR 0.76 [0.09, 5.9] | NR | Very low Downgraded: risk of bias, imprecision |
Cefixime (1 RCT; 38 participants) | HR 1.26 [0.26, 6.9] | NR | Very low Downgraded: risk of bias, imprecision |
Cefonicid (1 RCT; 60 participants) | HR 1.3 [0.52, 3.24] | NR | Very low Downgraded: risk of bias, imprecision |
Meropenem plus daptomycin (No direct RCT) | HR 0.64 [0.05, 6.13] | NR | Very low Downgraded: risk of bias, imprecision |
Ofloxacin (No direct RCT) | HR 0.56 [0.09, 2.93] | NR | Very low Downgraded: risk of bias, imprecision |
Liver transplantation | no estimate extracted | NR | No studies |
Ciprofloxacin (2 RCT; 275 participants) | HR 0.93 [0.69, 1.25] | NR | Very low Downgraded: risk of bias, imprecision |