Any ICS showed no clear difference in asthma relapse1at 16 to 21 days compared with oral corticosteroid (moderate certainty).
Any ICS showed no clear difference in hospital admission compared with oral corticosteroid (moderate certainty).
Any ICS showed no clear difference in hoarseness at 16 to 21 days compared with oral corticosteroid (low certainty).
Any ICS plus oral corticosteroid showed no clear difference in asthma relapse1at 20 to 24 days compared with oral corticosteroid (high certainty).
Any ICS plus oral corticosteroid showed no clear difference in hospital admission compared with oral corticosteroid (moderate certainty).
Any ICS plus oral corticosteroid showed no clear difference in hoarseness at 20 to 24 days compared with oral corticosteroid (moderate certainty).
It is very uncertain whether once‐daily ICS/LABA combined inhalers changes any COPD exacerbation that requires short‐burst oral corticosteroids… compared with once‐daily LAMA (very low certainty).
LABA + ICS probably leads to lower withdrawals for any reason compared with LTRA + ICS (moderate certainty).
Antibiotics showed no clear difference in any adverse event WMD of compared with placebo (moderate certainty).
Antibiotics showed no clear difference in adverse events ‐ overall (any adverse events not specified) compared with placebo overall (moderate certainty).
LAMA add‐on showed no clear difference in any adverse events 24 weeks compared with ICS alone (low certainty).
School‐based ICS therapy showed no clear difference in unscheduled visits 1 or more hospitalisations for any cause WMD of compared with home therapy (low certainty).
The intervention leads to lower any adverse events 49 weeks (high certainty).