Cochrane · systematic review · CD002316
Inhaled steroids for acute asthma following emergency department discharge
Edmonds, ML, Milan, SJ, Brenner, BE, et al. · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library
AirwaysAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 16.7%Moderate 4 · 66.7%High 1 · 16.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Any ICS plus oral corticosteroid versus oral corticosteroid for acute asthma following emergency department discharge
Population: predominantly adults with acute asthma following emergency department discharge
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Asthma relapse1at 20 to 24 days Any ICS plus oral corticosteroid vs oral corticosteroid | OR 0.68 [0.46, 1.02] | 3 studies · 909 participants | High |
Hospital admission Any ICS plus oral corticosteroid vs oral corticosteroid | OR 0.99 [0.39, 2.52] | 2 studies · 805 participants | Moderate Downgraded: imprecision, inconsistency |
Hoarseness at 20 to 24 days Any ICS plus oral corticosteroid vs oral corticosteroid | OR 0.6 [0.36, 1.01] | 2 studies · 596 participants | Moderate Downgraded: imprecision, inconsistency |
Any ICS versus oral corticosteroid for acute asthma following emergency department discharge
Population: patients with acute asthma following emergency department discharge
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Asthma relapse1at 16 to 21 days Any ICS vs oral corticosteroid | OR 1.26 [0.8, 1.99] | 2 studies · 425 participants | Moderate Downgraded: imprecision |
Hospital admission Any ICS vs oral corticosteroid | OR 0.31 [0.01, 7.95] | 3 studies · 254 participants | Moderate Downgraded: imprecision |
Hoarseness at 16 to 21 days Any ICS vs oral corticosteroid | OR 1.62 [0.52, 5.05] | 1 study · 412 participants | Low Downgraded: imprecision |