Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

144 questions · 145 findings · 16 reviews · Eyes and Vision

No studies found 46 · 31.7%GRADE not reported 0 · 0%Very low 30 · 20.7%Low 21 · 14.5%Moderate 44 · 30.3%High 4 · 2.8%

Summary of findings table ‐ Pseudophakia vs aphakia

Glaucoma at 5 years · children younger than two years of age with bilateral congenital cataracts

It is very uncertain whether summary of findings table ‐ Pseudophakia changes glaucoma at 5 years compared with aphakia (very low certainty).

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Motor alignment at near Change in exotropia control at near fixation, measured from baseline to 3 years using the prism and alternate cover test · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in motor alignment at near Change in exotropia control at near… compared with unilateral lateral rectus recession with medial rectus resection (moderate certainty).

1 finding from 1 review

Patching vs active observation

Stereoacuity at distance Loss of ≥ 2 octaves near stereoacuity Measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged less than 11 years

The review found no eligible studies for this question.

1 finding from 1 review

Patching vs active observation

Quality of life measures Measured at 3 years using the IXTQ scores for children, parents, or parent proxies (i.e. parents' perception of their children's quality of life). Scores could range from 0 (worst quality of life) to 100 (best quality of l... · people with intermittent exotropia, aged less than 11 years

The review found no eligible studies for this question.

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Stereoacuity at near Loss of ≥ 2 octaves near stereoacuity, measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in stereoacuity at near Loss of ≥ 2 octaves near stereoacuity, measured… compared with unilateral lateral rectus recession with medial rectus resection (low certainty).

1 finding from 1 review

Prism adaptation test with eye muscle surgery vs eye muscle surgery alone

Quality of life measures Measured at 3 years using the IXTQ scores for children, parents, or parent proxies (i.e. parents' perception of their children's quality of life). Scores could range from 0 (worst quality of life) to 100 (best quality of l... · people with intermittent exotropia, aged 5 to 49 years

The review found no eligible studies for this question.

1 finding from 1 review

Lateral rectus recession and medial rectus plication vs lateral rectus recession and medial rectus resection

Stereoacuity at distance Loss of ≥ 2 octaves near stereoacuity Measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged over 6 years

The review found no eligible studies for this question.

1 finding from 1 review

Lateral rectus recession and medial rectus plication vs lateral rectus recession and medial rectus resection

Quality of life measures Measured at 3 years using the IXTQ scores for children, parents, or parent proxies (i.e. parents' perception of their children's quality of life). Scores could range from 0 (worst quality of life) to 100 (best quality of l... · people with intermittent exotropia, aged over 6 years

The review found no eligible studies for this question.

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Motor alignment at distance Change in exotropia control at near fixation, measured from baseline to 3 years using the prism and alternate cover test · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in motor alignment at distance Change in exotropia control at near… compared with unilateral lateral rectus recession with medial rectus resection (moderate certainty).

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Quality of life measures Measured at 3 years using the IXTQ scores for children, parents, or parent proxies (i.e. parents' perception of their children's quality of life). Scores could range from 0 (worst quality of life) to 100 (best quality of l... · people with intermittent exotropia, aged 3 to < 11 years
1 finding from 1 review

Summary of findings table ‐ Pseudophakia vs aphakia

Visual axis opacification · children younger than two years of age with bilateral congenital cataracts

It is very uncertain whether summary of findings table ‐ Pseudophakia changes visual axis opacification compared with aphakia (very low certainty).

1 finding from 1 review