Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,016 questions · 2,067 findings · 222 reviews · Headline outcomes only

No studies found 471 · 22.8%GRADE not reported 108 · 5.2%Very low 570 · 27.6%Low 458 · 22.2%Moderate 363 · 17.6%High 97 · 4.7%

Summary of findings: quinolone prophylaxis vs TMP‐SMZ prophylaxis

Febrile patients and episodes · cancer patients with afebrile neutropenia following chemotherapy

Summary of findings: quinolone prophylaxis probably leads to lower febrile patients and episodes compared with TMP‐SMZ prophylaxis (moderate certainty).

1 finding from 1 review

Intervention not reported

Re‐infection · children with lower urinary tract infection

It is very uncertain whether the intervention changes re‐infection (very low certainty).

1 finding from 1 review

Intervention not reported

Persistent bacteriuria · children with lower urinary tract infection

It is very uncertain whether the intervention changes persistent bacteriuria (very low certainty).

1 finding from 1 review

Intervention not reported

Recurrence · children with lower urinary tract infection

It is very uncertain whether the intervention changes recurrence (very low certainty).

1 finding from 1 review