Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,092 questions · 3,199 findings · 339 reviews · Headline outcomes only

No studies found 714 · 22.3%GRADE not reported 181 · 5.7%Very low 695 · 21.7%Low 908 · 28.4%Moderate 568 · 17.8%High 133 · 4.2%

RISPERIDONE DEPOT vs OLANZAPINE

Adverse events: General ‐ serious · patients with schizophrenia

RISPERIDONE DEPOT showed no clear difference in adverse events: General ‐ serious compared with ORAL OLANZAPINE (low certainty).

1 finding from 1 review

RISPERIDONE DEPOT vs OLANZAPINE

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

RISPERIDONE DEPOT may leads to higher adverse events: Movement disorder ‐ any extra pyramidal symptoms compared with ORAL OLANZAPINE (low certainty).

1 finding from 1 review

RISPERIDONE DEPOT vs OLANZAPINE

Weight gain · patients with schizophrenia

RISPERIDONE DEPOT may leads to lower adverse events: Specific ‐ weight increase compared with ORAL OLANZAPINE (low certainty).

1 finding from 1 review

OUTBACK re‐entry catheter vs manual re‐entry

months' patency rate · 52 people with TASC‐II D superficial femoral artery chronic total occlusions

OUTBACK re‐entry catheter showed no clear difference in months' patency rate compared with manual re‐entry (low certainty).

2 findings from 1 review

OUTBACK re‐entry catheter vs manual re‐entry

Primary patency ( · 52 people with TASC‐II D superficial femoral artery chronic total occlusions
2 findings from 1 review

Breastfeeding vs other interventions, oral water, or no treatment

All pain scores during injection Due to range of pain scores used, data analysed using SMDs. Pain scores were measured during and up to 3 minutes following completion of vaccination. · Infants 1 to 12 months during vaccination
2 findings from 1 review

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics

Resolution of ear discharge at short‐term

Antibiotic eardrops (with or without a corticosteroid) probably leads to higher resolution of ear discharge at short‐term compared with oral antibiotics (moderate certainty).

1 finding from 1 review