Question · asked by 1 review

Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics: Adverse events

Population
Not specified
Intervention
Antibiotic eardrops (with or without a corticosteroid)
Comparison
oral antibiotics
Outcome
Adverse events

Antibiotic eardrops (with or without a corticosteroid) showed no clear difference in adverse events compared with oral antibiotics (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Antibiotic eardrops (with or without a corticosteroid) vs oral antibiotics
Adverse events
Antibiotic eardrops (with or without a corticosteroid) showed no clear difference in adverse events compared with oral antibiotics (low certainty).
Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation… (2016) · Cochrane Headline outcomes only
RR 0.37 [0.12, 1.09]3 studies · 705 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for children with ear discharge occurring at least two weeks following grommet (ventilation tube) insertion
2016 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.