Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,536 questions · 2,637 findings · 315 reviews

No studies found 608 · 23.1%GRADE not reported 488 · 18.5%Very low 688 · 26.1%Low 540 · 20.5%Moderate 249 · 9.4%High 64 · 2.4%

Clobetasol propionate cream vs prednisone

Adverse events: severe complications at day 21 · bullous pemphigoid

Clobetasol propionate cream may leads to lower adverse events: severe complications at day 21 compared with oral prednisone (low certainty).

1 finding from 1 review

Doxycycline vs prednisolone

Disease control · bullous pemphigoid

Doxycycline leads to lower disease control at 6 weeks (unadjusted raw data) compared with prednisolone (high certainty).

1 finding from 1 review

Application of heat vs application of cold

At least a clinically significant reduction in pain within 6 hours Reported in studies as: clinically improved or reduced pain,a or cessation of pain at end of treatmentb · people stung accidentally by bluebottle jellyfish (Physalia) and box jellyfish that do not cause Irukandji syndrome (Hawaiian box…

It is very uncertain whether application of heat changes at least a clinically significant reduction in pain within 6 hours… compared with application of cold (very low certainty).

1 finding from 1 review

Intervention not reported

Clinically significant reduction in pain · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Cessation of pain at end of treatmenta · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…
1 finding from 1 review

Intervention not reported

Dermatological signs up to 1 week after the sting · people stung accidentally by box jellyfish that do not cause Irukandji syndrome (Hawaiian box jellyfish; Carybdea alata) and healthy…

The review found no eligible studies for this question.

1 finding from 1 review