Question · asked by 1 review

Doxycycline vs prednisolone: Disease control

Population
bullous pemphigoid
Intervention
Doxycycline
Comparison
prednisolone
Outcome
Disease control

Doxycycline leads to lower disease control at 6 weeks (unadjusted raw data) compared with prednisolone (high certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Doxycycline vs prednisolone
Disease control at 6 weeks (unadjusted raw data) · bullous pemphigoid
Doxycycline leads to lower disease control at 6 weeks (unadjusted raw data) compared with prednisolone (high certainty).
Interventions for bullous pemphigoid (2023) · Cochrane Headline outcomes only
RR 0.81 [0.72, 0.92]1 study · 213 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for bullous pemphigoid
2023 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.