Findings

What do systematic reviews say?

3,696 questions · 3,815 findings · 855 reviews

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No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Effects of school‐based asthma interventions vs usual care

Experience of daytime and night‐time symptoms ‐ daytime symptoms (daytime symptoms) · children with asthma

1 finding from 1 review

School‐based self‐management interventions for asthma in children and adolescents: a mixed methods systematic review 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1065 participants
Moderate

Needle aspiration (needle removed immediately after aspiration) vs intercostal tube drainage

Neonatal mortality · patients with pneumothorax in the newborn

The review found no eligible studies for this question.

1 finding from 1 review

Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Needle aspiration (needle or angiocatheter left in situ) vs intercostal tube drainage

Neonatal mortality · patients with pneumothorax in the newborn

The review found no eligible studies for this question.

1 finding from 1 review

Needle aspiration versus intercostal tube drainage for pneumothorax in the newborn 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Duration of upper gastrointestinal bleeding (days) · infants with upper gastrointestinal bleeding

1 finding from 1 review

Pharmacological interventions for prevention and treatment of upper gastrointestinal bleeding in newborn infants 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 104 participants
Very low

Primary (complete) wound closure vs delayed closure

Proportion of wounds which were infection‐free · patients with traumatic wounds due to dog bite

It is very uncertain whether primary closure changes proportion of wounds which were infection free on day 7 compared with delayed closure (very low certainty).

1 finding from 1 review

Primary closure versus delayed or no closure for traumatic wounds due to mammalian bite 2019 · Cochrane Headline outcomes only
RR 0.98 [0.9, 1.07]
1 study · 120 participants
Very low

Robotic‐assisted laparoscopic vs open radical cystectomy

Length of hospital stay · bladder cancer in adults

1 finding from 1 review

Robotic versus open radical cystectomy for bladder cancer in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 541 participants
Low

Omega‐3 fatty acids and antioxidants vs standard diet or placebo

Duration of ICU stay · adults (aged 18 years or older), mechanically ventilated participants with ARDS as defined by the Berlin definition of ARDS or, for older…

1 finding from 1 review

Immunonutrition for acute respiratory distress syndrome (ARDS) in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 639 participants
Very low

Omega‐3 fatty acids and antioxidants vs standard diet or placebo

Days on ventilator · adults (aged 18 years or older), mechanically ventilated participants with ARDS as defined by the Berlin definition of ARDS or, for older…

1 finding from 1 review

Immunonutrition for acute respiratory distress syndrome (ARDS) in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 581 participants
Very low

Omega‐3 fatty acids and antioxidants vs standard diet or placebo

Indices of oxygenation (measured as PaO₂/FiO₂ ratio at day 4) · adults (aged 18 years or older), mechanically ventilated participants with ARDS as defined by the Berlin definition of ARDS or, for older…

1 finding from 1 review

Immunonutrition for acute respiratory distress syndrome (ARDS) in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 659 participants
Very low

Fexofenadine 120 mg/d vs placebo (1‐week intervention)

Pruritus · adults with eczema

1 finding from 1 review

Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 400 participants
Moderate

Zinc tape vs gauze soaked

Ulcer healing · ulceration caused by nerve damage in leprosy

1 finding from 1 review

Interventions for ulceration and other skin changes caused by nerve damage in leprosy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 90 participants
Very low

Psychological therapies vs controls

Migraine frequency Number of attacks · adults with migraine

1 finding from 1 review

Psychological therapies for the prevention of migraine in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 681 participants
Very low

Continuous local anaesthetic wound infusion vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing elective midline laparotomy for colorectal resection

1 finding from 1 review

Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 511 participants
High

Continuous local anaesthetic wound infusion vs placebo

Pain (VAS scores) on movement at postoperative day 1 Scale from: 0 to 10. · adults undergoing elective midline laparotomy for colorectal resection

1 finding from 1 review

Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 407 participants
Low

Continuous local anaesthetic wound infusion vs placebo

Opioid consumption via patient controlled analgesia postoperative day 1 · adults undergoing elective midline laparotomy for colorectal resection

1 finding from 1 review

Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 528 participants
Moderate

Continuous local anaesthetic wound infusion vs placebo

Time to first BM (№ women with 1st BM on day 2 after delivery) · adults undergoing elective midline laparotomy for colorectal resection

1 finding from 1 review

Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 197 participants
Moderate

Continuous local anaesthetic wound infusion vs placebo

Length of hospital stay · adults undergoing elective midline laparotomy for colorectal resection

1 finding from 1 review

Continuous local anaesthetic wound infusion for postoperative pain after midline laparotomy for colorectal resection… 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 456 participants
High

Early enteral nutrition vs delayed enteral nutrition

Mortality (measured at 30 days) · critically ill adult patients

It is very uncertain whether early enteral nutrition changes mortality (measured at 30 days) compared with delayed enteral nutrition (very low certainty).

1 finding from 1 review

Early enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without… 2019 · Cochrane Headline outcomes only
RR 1 [0.16, 6.38]
1 study · 38 participants
Very low

Early enteral nutrition with supplemental parenteral nutrition (SPN) vs delayed enteral nutrition with SPN

Length of hospital stay · critically ill adult patients

The review found no eligible studies for this question.

1 finding from 1 review

Early enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Early enteral nutrition with supplemental parenteral nutrition (SPN) vs delayed enteral nutrition with SPN

Duration of mechanical ventilation · critically ill adult patients

1 finding from 1 review

Early enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without… 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 27 participants
Very low