Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,355 questions · 2,459 findings · 279 reviews

No studies found 556 · 22.6%GRADE not reported 490 · 19.9%Very low 593 · 24.1%Low 479 · 19.5%Moderate 243 · 9.9%High 98 · 4%

Intervention not reported

Finding 14. Finding the right support could facilitate participation and encourage men and women to be active. Having support, whether from professionals or friends and family, was important. · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

Intervention not reported

Finding 15. Mood regulation is an important aspect of managing symptoms of bipolar disorder, and monitoring mood and physical activity, including the use of technology, may be helpful for men and women with bipolar disorder. This can be used to he... · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

Intervention not reported

Finding 16. Accessible, sustainable interventions and finding the right type of exercise were all identified as important. For many women and men with bipolar disorder, the right type of exercise was walking. · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

Intervention not reported

Finding 17. Finding balance, rhythm, structure, and establishing a regular physical activity routine was beneficial. Rhythm and routine brought balance and structure for men and women with bipolar disorder. Incorporating regular physical activity ... · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

Intervention not reported

Finding 18: Appropriate coping strategies may support engagement in physical activity and other health‐promoting behaviours. Negative coping mechanisms or a lack of coping strategies for men and women with bipolar disorder can affect engagement. P... · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

Intervention not reported

Finding 19: Connecting to nature when undertaking physical activity may convey additional benefits, including increasing the opportunity for social contact, engaging with nature, and reducing stress, that are often associated with spending time ou... · s where they do not wish or feel the need to participate in physical activity.
1 finding from 1 review

Minimally invasive caries removal (MIT): selective removal to soft dentin, self-limiting chemomechanical removal, or partial/incomplete caries removal vs Conventional caries removal (CT): selective removal to firm dentin, stepwise excavation, or complete caries removal

Treatment success (caries lesion arrest or restoration survival) · Patients with deep carious lesions in permanent (mainly posterior) teeth

Minimally invasive caries removal showed a marginally higher mean restoration success rate than conventional removal (83.6% vs 75.4%), but the difference was not statistically significant (Mann-Whitney U, p > 0.05); certainty of evidence was not graded.

1 finding from 1 review

nCaF2 primer vs Control Transbond primer

Streptococcus mutans count · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

nCaF2 primer differed in S. mutans count only at T1, with certainty not graded.

1 finding from 1 review

Clearfil Protect Bond antibacterial fluoride-releasing primer vs Conventional Transbond XT primer

Bracket (bond) failure · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

Clearfil Protect Bond showed no difference in bracket failure, with certainty not graded.

1 finding from 1 review

TiO2-modified composite (1 wt.%) vs Control composite in contralateral quadrant

Enamel demineralization (DIAGNOdent score) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

TiO2-modified composite favored lower DIAGNOdent scores, with certainty not graded.

1 finding from 1 review

Chlorhexidine mouthwash vs placebo

Cariogenic bacteria (Mutans streptococci) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

Chlorhexidine mouthwash reduced Mutans streptococci versus placebo, but certainty is very low.

1 finding from 1 review

Chlorhexidine mouthwash vs Blank control

Cariogenic bacteria (Mutans streptococci) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

Chlorhexidine mouthwash reduced Mutans streptococci versus blank control, but certainty is very low.

1 finding from 1 review

Herbal mouthwash vs placebo

Plaque · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

Herbal mouthwash reduced some plaque-related indices versus placebo, with low-certainty evidence.

1 finding from 1 review

Fluoride mouthwash vs Blank control

Cariogenic bacteria (Mutans streptococci) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

Short-term fluoride mouthwash reduced Mutans streptococci, but certainty is very low.

2 findings from 1 review

Chlorhexidine mouthwash vs Placebo mouthwash

Probing pocket depth (PPD/PD) · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)

Chlorhexidine mouthwash may reduce pocket probing depth versus placebo in the short term (low certainty).

1 finding from 1 review

Chlorhexidine mouthwash vs Blank control

Plaque · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)

Chlorhexidine mouthwash may reduce the Plaque Index versus blank control in the short term (WMD -0.70, 95% CI -1.12 to -0.27), but the evidence is very uncertain (very low certainty).

1 finding from 1 review

Cetylpyridinium chloride mouthwash vs Blank control

Plaque · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)

CPC mouthwash may reduce plaque-related indexes versus blank control in the short term, but the evidence is very uncertain (very low certainty).

1 finding from 1 review

Herbal mouthwash vs placebo

Cariogenic bacteria (Mutans streptococci) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)

Herbal mouthwash reduced Mutans streptococci versus placebo, but certainty is very low.

1 finding from 1 review

Fluoride mouthwash vs Blank control

Gingival inflammation-related index · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)

Short-term fluoride mouthwash has uncertain effects on gingival inflammation-related indexes versus blank control (very low certainty).

1 finding from 1 review