Question · asked by 1 review

Chlorhexidine mouthwash vs Placebo mouthwash: Probing pocket depth (PPD/PD)

Population
Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances)
Intervention
Chlorhexidine mouthwash
Comparison
Placebo mouthwash
Outcome
Probing pocket depth (PPD/PD)

Chlorhexidine mouthwash may reduce pocket probing depth versus placebo in the short term (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Chlorhexidine (CHX) mouthwash (adjunct to mechanical cleaning) vs Placebo mouthwash
Pocket probing depth (PD) · Orthodontic patients (any age) undergoing orthodontic treatment (mostly fixed appliances) · <=3 months (short-term), Orthodontic patients undergoing orthodontic treatment (randomized controlled trials; multiple countries)
Chlorhexidine mouthwash may reduce pocket probing depth versus placebo in the short term (low certainty).
The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic… (2023) All outcomes
PD was significantly reduced except mid-lingual site compared to placebo [32]. The changes of PD were significantly higher compared to placebo [56].2 studiesLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
The efficacy of mouthwashes on oral microorganisms and gingivitis in patients undergoing orthodontic treatment: a systematic review and…
2023 All outcomes
16 April 2022 (databases and grey literature searched by 16 April 2022; no publication-year limit)47Low / Moderate
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.