Bacteriologic Cure · patients with Clostridium difficile‐associated diarrhoea in adults
It is very uncertain whether metronidazole changes bacteriologic cure compared with vancomycin (very low certainty).
1 finding from 1 review
Cure (combined symptomatic and bacteriologic cure) ‐ mild disease · patients with Clostridium difficile‐associated diarrhoea in adults
It is very uncertain whether metronidazole changes cure (combined symptomatic and bacteriologic cure) ‐ mild disease compared with vancomycin (very low certainty).
1 finding from 1 review
Cure (combined symptomatic and bacteriologic cure) ‐ severe disease · patients with Clostridium difficile‐associated diarrhoea in adults
It is very uncertain whether metronidazole changes cure (combined symptomatic and bacteriologic cure) ‐ severe disease compared with vancomycin (very low certainty).
1 finding from 1 review
Symptomatic Cure · patients with Clostridium difficile‐associated diarrhoea in adults
It is very uncertain whether teicoplanin changes symptomatic Cure compared with vancomycin (very low certainty).
1 finding from 1 review
Bacteriologic Cure · patients with Clostridium difficile‐associated diarrhoea in adults
It is very uncertain whether teicoplanin changes bacteriologic Cure compared with vancomycin (very low certainty).
1 finding from 1 review
Symptomatic Cure · patients with Clostridium difficile‐associated diarrhoea in adults
Fidaxomicin probably leads to higher symptomatic Cure compared with vancomycin (moderate certainty).
1 finding from 1 review
Symptomatic Cure · patients with Clostridium difficile‐associated diarrhoea in adults
It is very uncertain whether bacitracin changes symptomatic Cure compared with vancomycin (very low certainty).
1 finding from 1 review
Intervention not reported
Total postoperative infections ‐ early and late Urinary tract infection Pelvic infection Other serious infections Postoperative fever · women having elective vaginal hysterectomy
It is very uncertain whether the intervention changes total postoperative infections ‐ early and late Urinary tract… (very low certainty).
1 finding from 1 review
Intervention not reported
Total adverse effects · women having elective vaginal hysterectomy
1 finding from 1 review
Intervention not reported
Total postoperative infections ‐ early and late Abdominal wound infection Urinary tract infection Pelvic infection Other serious infections Postoperative fever · women having elective abdominal hysterectomy
1 finding from 1 review
Intervention not reported
Total adverse effects · women having elective abdominal hysterectomy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Death ‐ in all participants ‐ short term · people suspected to have meningococcal disease (adults and children)
Ceftriaxone showed no clear difference in death ‐ in all participants ‐ short term compared with long‐acting (oily) chloramphenicol (moderate certainty).
1 finding from 1 review
Death ‐ in confirmed cases of meningococcal meningitis (subgroup) · people suspected to have meningococcal disease (adults and children)
Ceftriaxone showed no clear difference in death ‐ in confirmed cases of meningococcal meningitis (subgroup) compared with long‐acting (oily) chloramphenicol (moderate certainty).
1 finding from 1 review
Clinical failure ‐ in all participants ‐ short term Composite clinical criteria10 · people suspected to have meningococcal disease (adults and children)
Ceftriaxone showed no clear difference in clinical failure ‐ in all participants ‐ short term Composite… compared with long‐acting (oily) chloramphenicol (moderate certainty).
1 finding from 1 review
Clinical failure ‐ in confirmed cases of meningococcal meningitis (subgroup) Composite clinical criteria10 · people suspected to have meningococcal disease (adults and children)
Ceftriaxone showed no clear difference in clinical failure ‐ in confirmed cases of meningococcal meningitis… compared with long‐acting (oily) chloramphenicol (moderate certainty).
1 finding from 1 review
Neurological sequelae ‐ in all participants‐ short term Clinical assessment11 · people suspected to have meningococcal disease (adults and children)
Ceftriaxone showed no clear difference in neurological sequelae ‐ in all participants‐ short term Clinical… compared with long‐acting (oily) chloramphenicol (low certainty).
1 finding from 1 review
Neurological sequelae ‐ in confirmed cases of meningococcal meningitis (subgroup) Clinical assesment11 · people suspected to have meningococcal disease (adults and children)
It is very uncertain whether ceftriaxone changes neurological sequelae ‐ in confirmed cases of meningococcal… compared with long‐acting (oily) chloramphenicol (very low certainty).
1 finding from 1 review
Adverse events ‐ short term · people suspected to have meningococcal disease (adults and children)
1 finding from 1 review
Intervention not reported
Comparison (intervention vs comparator) · participants undergoing cataract surgery
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Treatment 2: topical regimen alone (chloramphenicol‐sulfadimidine) · participants undergoing cataract surgery
1 finding from 1 review
no estimate extracted
6618 participants
Moderate