Major bleeding · patients undergoing non‐cardiac surgery/invasive procedures
It is very uncertain whether thromboelastography threshold changes major bleeding within 24 hours № of participants: 60 (1 RCT) compared with standard of care (laboratory parameters) (very low certainty).
1 finding from 1 review
RR 0.33 [0.01, 7.87]
Studies not reported
Very low
Number of transfusions per participant within 7 days ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of individuals requiring a transfusion within 7 days № of participants: 60 (1 RCT) · patients undergoing non‐cardiac surgery/invasive procedures
Thromboelastography threshold may leads to lower number of individuals requiring a transfusion within 7 days № of… compared with standard of care (laboratory parameters) (low certainty).
1 finding from 1 review
RR 0.18 [0.08, 0.39]
Studies not reported
Low
Serious adverse events measured by plasma transfusion‐related complications within 24 hours № of participants: 21 (1 RCT) · patients undergoing non‐cardiac surgery/invasive procedures
It is very uncertain whether thromboelastography threshold changes serious adverse events measured by plasma transfusion‐related… compared with standard of care (laboratory parameters) (very low certainty).
1 finding from 1 review
RR 0.33 [0.01, 7.87]
Studies not reported
Very low
Quality of life ‐ not reported · patients undergoing non‐cardiac surgery/invasive procedures
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Major complications · adults receiving intravenous fluids while undergoing major non‐cardiac surgery
It is very uncertain whether perioperative restrictive fluid therapy changes major complications (during longest compared with goal‐directed fluid therapy (very low certainty).
1 finding from 1 review
Mortality within the longest · adults receiving intravenous fluids while undergoing major non‐cardiac surgery
It is very uncertain whether perioperative restrictive fluid therapy changes all‐cause mortality (during longest compared with goal‐directed fluid therapy (very low certainty).
1 finding from 1 review
Length of hospital stay · adults receiving intravenous fluids while undergoing major non‐cardiac surgery
It is very uncertain whether perioperative restrictive fluid therapy changes length of hospital stay (days) compared with goal‐directed fluid therapy (very low certainty).
1 finding from 1 review
Renal failure · adults receiving intravenous fluids while undergoing major non‐cardiac surgery
It is very uncertain whether perioperative restrictive fluid therapy changes renal failure (during longest compared with goal‐directed fluid therapy (very low certainty).
1 finding from 1 review
Quality of surgical recovery assessed in any way (e.g. as a surgical recovery score) (during longest · adults receiving intravenous fluids while undergoing major non‐cardiac surgery
1 finding from 1 review
Pain · children having undergone thoraco‐lumbar spine surgery. 3 trials included in the analysis contained participants older than 18 years:…
1 finding from 1 review
Return of gastrointestinal function · children having undergone thoraco‐lumbar spine surgery. 3 trials included in the analysis contained participants older than 18 years:…
It is very uncertain whether epidural analgesia changes return of gastrointestinal function compared with systemic analgesia (very low certainty).
1 finding from 1 review
Time to first mobilisation · children having undergone thoraco‐lumbar spine surgery. 3 trials included in the analysis contained participants older than 18 years:…
1 finding from 1 review
Length of hospital stay · children having undergone thoraco‐lumbar spine surgery. 3 trials included in the analysis contained participants older than 18 years:…
1 finding from 1 review
Satisfaction with postoperative analgesia regimen · children having undergone thoraco‐lumbar spine surgery. 3 trials included in the analysis contained participants older than 18 years:…
1 finding from 1 review
Complications · children having undergone thoraco‐lumbar spine surgery. 3 trials included in the analysis contained participants older than 18 years:…
It is very uncertain whether epidural analgesia changes complications compared with systemic analgesia (very low certainty).
1 finding from 1 review
Menopause‐specific quality of life (quality of life) · female BRCA carriers post‐risk‐reducing surgery
1 finding from 1 review
Effect on later sexual function · adult women, 18 years of age or older, who tested positive for a pathogenic mutation in BRCA1 or BRCA2 and who had had risk‐reducing surgery
1 finding from 1 review
Body image · adult women, 18 years of age or older, who tested positive for a pathogenic mutation in BRCA1 or BRCA2 and who had had risk‐reducing surgery
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Sexual self‐efficacy scale · adult women, 18 years of age or older, who tested positive for a pathogenic mutation in BRCA1 or BRCA2 and who had had risk‐reducing surgery
1 finding from 1 review