Cochrane · systematic review · CD012819
Postoperative epidural analgesia versus systemic analgesia for thoraco‐lumbar spine surgery in children
Guay, J, Suresh, S, Kopp, S, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 5 · 71.4%Low 1 · 14.3%Moderate 1 · 14.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Epidural analgesia compared to systemic analgesia for postoperative analgesia after thoraco‐lumbar spine surgery in children
Population: children having undergone thoraco‐lumbar spine surgery. 3 trials included in the analysis contained participants older than 18 years: Blumenthal 2005 (10–30 years; mean age 17 years), Klatt 2013 (10–21 years), and O'Hara 2004 (13–21 years)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Pain Epidural analgesia vs systemic analgesia | no estimate extracted | 4 studies · 116 participants | Moderate Downgraded: risk of bias |
Vomiting up to 48 hours after surgery Epidural analgesia vs systemic analgesia | RR 0.87 [0.58, 1.3] | 6 studies · 215 participants | Low Downgraded: risk of bias, imprecision |
Return of gastrointestinal function Epidural analgesia vs systemic analgesia | RR 1.63 [1.08, 2.47] | 1 study · 30 participants | Very low Downgraded: risk of bias, imprecision |
Time to first mobilization: time ambulate (days) Epidural analgesia vs systemic analgesia | no estimate extracted | 1 study · 60 participants | Very low Downgraded: risk of bias, imprecision |
Hospital length of stay (days) Epidural analgesia vs systemic analgesia | no estimate extracted | 2 studies · 89 participants | Very low Downgraded: risk of bias, imprecision |
Satisfaction with postoperative analgesia regimen Epidural analgesia vs systemic analgesia | no estimate extracted | 2 studies · 60 participants | Very low Downgraded: risk of bias, imprecision |
Complications Epidural analgesia vs systemic analgesia | no estimate extracted | 4 studies · 126 participants | Very low Downgraded: risk of bias, imprecision |