Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,315 questions · 23,557 findings · 2,311 reviews

No studies found 4,183 · 17.8%GRADE not reported 3,930 · 16.7%Very low 5,371 · 22.8%Low 5,787 · 24.6%Moderate 3,320 · 14.1%High 966 · 4.1%

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Human chorionic gonadotropin (hCG) injection vs no treatment

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes multiple pregnancy rate compared with no treatment (very low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Clinical pregnancy per woman ‐ oral route · women trying to conceive by intrauterine insemination

It is very uncertain whether progesterone changes clinical pregnancy per woman ‐ oral route compared with no treatment or placebo (route of progesterone administration) (very low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in multiple pregnancy per woman compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: 1. Sedation · patients with motion sickness

Antihistamines may leads to higher adverse effects: sedation Assessed by: adverse effect questionnaire… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects: impaired cognition Assessed by: adverse effect questionnaire (presence or absence given numerical values) · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: impaired cognition Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Antihistamines vs placebo

Adverse effects ‐ Blurred vision No of patients with blurred vision · patients with motion sickness

Antihistamines showed no clear difference in adverse effects: blurred vision Assessed by: adverse effect… compared with placebo (low certainty).

1 finding from 1 review

Whole‐facility changes: Home‐like models vs traditional environment

Depression Revised Memory and Behaviour Problems Checklist (RMBPC) and Mood Scale Score (MSS) (lower scores = better) · older adults living in long‐term residential care including, but not limited to, dementia‐specific care settings
1 finding from 1 review

Intervention not reported

Knowledge and understanding Variable scales: information (amount and type) needs/preferences; discordance between patient and physician survival and curability estimates Timing: immediately to 1 month post‐consultation · people approaching the end of life (within 12 months), their family members and/or carers
1 finding from 1 review

Intervention not reported

Evaluation of the communication: different constructs (perceptions of communication quality; patient‐centredness of communication; involvement preferences; doctor‐patient relationship measures) Timing: immediately post‐consultation to 18 weeks pos... · people approaching the end of life (within 12 months), their family members and/or carers
1 finding from 1 review