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Evidence found and GRADE certainty

358 questions · 403 findings · 68 reviews

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No studies found 43 · 10.7%GRADE not reported 121 · 30%Very low 128 · 31.8%Low 66 · 16.4%Moderate 33 · 8.2%High 12 · 3%

Bio-active restorative materials vs Any conventional restorative material

Treatment failure (planned; no eligible studies) · Children with carious primary teeth after vital or non-vital pulp therapy

No eligible studies were found evaluating bio-active restorative materials for restoring carious primary teeth after pulp therapy.

1 finding from 1 review

Dental caries assessment (WHO/clinical diagnostic criteria; caries = DMFT>0) vs None (descriptive prevalence meta-analysis)

Dental caries prevalence · General Pakistani population (all ages and both sexes; predominantly children and adolescents)

In permanent dentition, the pooled prevalence of dental caries was 57.2% (95% CI 26.3 to 85.3); ungraded.

10 findings from 1 review
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Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Vegetable consumption behaviour: proportion in the Action Stage of Change (versus Pre-Action) · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Fruit consumption · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Body‐mass index (BMI) · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Vegetable consumption (grams per day) · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Fruit juice consumption: risk of starting to drink fruit juice · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK

Dietary counselling tailored to a Stage of Change (Transtheoretical… showed no clear difference in fruit juice consumption: risk of starting to drink fruit juice compared with usual care; GRADE not reported.

1 finding from 1 review

Dietary counselling tailored to a Stage of Change (Transtheoretical Model) to increase fruit and vegetable intake (two counselling sessions) vs usual care

Fruit consumption behaviour: proportion in the Action Stage of Change (versus Pre-Action) · Edentulous patients aged 45 to 80 years attending dental-student teaching clinics for replacement dentures, Newcastle Dental Hospital, UK
1 finding from 1 review

Ion-releasing restorations (IRR): RMGIC, HVGIC, GIC, compomer/PMRC, giomer vs Composite resin (CR), including bulk-fill composite

Proper surface staining · Children receiving dental restorations (aged 4-11 years; primary teeth; Class I/II/V cavities)

No significant difference between IRR and CR in surface staining (moderate certainty; downgraded for inconsistency).

1 finding from 1 review

Oral methotrexate plus intra‐articular glucocorticoid vs intra‐articular glucocorticoid alone

Sustained clinically inactive diseasec · children and young people with JIA

Oral methotrexate plus intra‐articular glucocorticoid showed no clear difference in sustained clinically inactive diseaseb(12 months) compared with intra‐articular glucocorticoid alone (low certainty).

1 finding from 1 review

Silver diamine fluoride (SDF) vs Other methods (pooled: ART/glass ionomer cement, nano-silver fluoride, sodium fluoride varnish, placebo)

Adverse effects (tooth staining and other side effects) · Children and adults with active dental caries (aged 1-50; mostly preschool/school children with primary dentition)

SDF commonly causes black staining of arrested lesions; only mild, transient adverse events were reported, with no major adverse events (ungraded).

1 finding from 1 review

38% SDF (indirect pulp capping) vs Resin-modified glass ionomer cement (RMGIC)

Restoration color, marginal staining and luster (esthetics) · Children with deep occlusal caries in young permanent first molars (indirect pulp capping)

RMGIC gave significantly better restoration esthetics than SDF, which caused black staining (p=0.03; ungraded).

1 finding from 1 review

Silver diamine fluoride (SDF) vs Not applicable (single-arm safety outcome)

Adverse events: black staining of arrested lesions · Children and older adults treated with SDF for carious lesions

Black staining of arrested lesions was the main adverse event of SDF (reported by seven reviews); it was generally acceptable to patients (ungraded).

1 finding from 1 review

Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in conjunction with mechanical oral hygiene procedures vs Placebo/control mouthrinse, or no mouthrinse (mechanical oral hygiene alone); controls pooled (protocol's separate comparisons versus mechanical oral hygiene alone and versus placebo/control merged)

Extrinsic tooth staining (various staining indices) · Children or adults with gingivitis or periodontitis capable of performing normal mechanical oral hygiene procedures (some with medical…

Chlorhexidine mouthrinse (any concentration; 0.05% to 0.2%) used in… led to higher extrinsic tooth staining (various staining indices) compared with placebo/control mouthrinse, or no mouthrinse (mechanical oral…; GRADE not reported.

2 findings from 1 review