Question · asked by 1 review
Silver diamine fluoride (SDF) vs Not applicable (single-arm safety outcome): Adverse events: black staining of arrested lesions
- Population
- Children and older adults treated with SDF for carious lesions
- Intervention
- Silver diamine fluoride (SDF)
- Comparison
- Not applicable (single-arm safety outcome)
- Outcome
- Adverse events: black staining of arrested lesions
Black staining of arrested lesions was the main adverse event of SDF (reported by seven reviews); it was generally acceptable to patients (ungraded).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Silver diamine fluoride vs Not applicable (single-arm safety outcome) Adverse events: black staining of arrested lesions · Children and older adults treated with SDF for carious lesions Black staining of arrested lesions was the main adverse event of SDF (reported by seven reviews); it was generally acceptable to patients (ungraded). Silver diamine fluoride for managing carious lesions: an umbrella review. (2019) All outcomes | Eight systematic reviews reported adverse events; seven reported black staining of arrested carious lesions. Older adults rarely complained; discoloration was acceptable in children, concerning 7% of participants in… | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Silver diamine fluoride for managing carious lesions: an umbrella review. 2019 All outcomes | June 2018 | 15 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.