Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

380 questions · 393 findings · 51 reviews

No studies found 96 · 24.4%GRADE not reported 45 · 11.5%Very low 64 · 16.3%Low 77 · 19.6%Moderate 63 · 16%High 48 · 12.2%

Intervention not reported

Autism symptom severity Measured by: parent‐reported autism symptoms on standardised autism screening and diagnostic instruments (lower scores indicate less severe autism symptoms) · patients with young children (less than six years old) with autism spectrum disorders (ASD)
1 finding from 1 review

Intervention not reported

Behavioural outcome: breast cancer screening Multimodal/complex intervention versus usual care at 12 months · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention leads to higher behavioural outcome: breast cancer screening Multimodal/complex… (high certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: breast cancer screening IVR versus enhanced usual care at median · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention showed no clear difference in behavioural outcome: breast cancer screening IVR versus enhanced… (moderate certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: colorectal cancer screening Multimodal/complex intervention versus usual care at median · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention leads to higher behavioural outcome: colorectal cancer screening Multimodal/complex… (high certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: colorectal cancer screening IVR versus usual care at 6‐month · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention probably leads to higher behavioural outcome: colorectal cancer screening IVR versus usual… (moderate certainty).

1 finding from 1 review

Intervention not reported

Behavioural outcome: colorectal cancer screening IVR, unidirectional ATCS versus usual care or letter at longer (9‐12 months) · participants at risk for breast, colorectal or cervical cancer; or osteoporosis

The intervention showed no clear difference in behavioural outcome: colorectal cancer screening IVR, unidirectional… (moderate certainty).

1 finding from 1 review

Summary of findings: multimedia education vs no education or usual care

Health outcomes: Drug misuse and dependence CAGE screening tool. Scale from 0 to 4. Higher score indicates greater probability of drug misuse or dependence · patients taking prescribed and over‐the‐counter medications or their carers
1 finding from 1 review

Intervention not reported

Perception ‐ screening message (measured as rating on a scale of perceived effectiveness) · consumers
1 finding from 1 review

Intervention not reported

Persuasiveness ‐ screening message (measured as a hypothetical decision or intention or willingness to adopt an intervention) · consumers
1 finding from 1 review

Toluidine blue (visual staining) vs No screening

Outcome not reported · Planned population: general population or high-risk / opportunistic screening groups (no eligible study)

The review found no eligible studies for this question.

1 finding from 1 review

Brush biopsy (oral cytology) vs No screening

Outcome not reported · Planned population: general population or high-risk / opportunistic screening groups (no eligible study)

The review found no eligible studies for this question.

1 finding from 1 review

Fluorescence imaging / light-based techniques vs No screening

Outcome not reported · Planned population: general population or high-risk / opportunistic screening groups (no eligible study)

The review found no eligible studies for this question.

1 finding from 1 review

Decision aids for informed consent vs usual care

Congruence between informed values and choice ‐ all studies Based on the proportion of participants who made a decision that aligned with what was most important to them. Assessed soon after exposure to the decision aid. · adults considering treatment or screening decisions

Patient decision aids probably leads to higher congruence between informed values and choice ‐ all studies Based on… compared with usual care (moderate certainty).

1 finding from 1 review