What do systematic reviews say?

Prone vs supine

• Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Very low

Summary of findings table ‐ Supine vs good‐lung independent

The review found no eligible studies for this question.

• Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

The review found no eligible studies for this question.

• Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

The review found no eligible studies for this question.

• Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Prone vs supine

• Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 121 participants
  Very low

Summary of findings table ‐ Supine vs good‐lung dependent

The review found no eligible studies for this question.

• Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Remifentanil vs diazepam

• Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 50 participants
  Low

Pulmonary rehabilitation vs usual care

• Pulmonary rehabilitation versus usual care for adults with asthma 2022 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 129 participants
  Very low

Nebulised magnesium sulfate + standard care vs placebo + standard care

• Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Very low

Magnesium sulfate vs ipratropium

The review found no eligible studies for this question.

• Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intravenous magnesium sulfate + standard care vs placebo + standard care

• Magnesium sulfate for acute exacerbations of chronic obstructive pulmonary disease 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 77 participants
  Very low

Prophylactic or very early CPAP vs supportive care

It is very uncertain whether prophylactic or very early CPAP changes failed treatment defined as recurrent apnoea, hypoxia, hypercarbia… compared with supportive care (very low certainty).

• Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
  RR 0.6 [0.49, 0.74]
  4 studies · 765 participants
  Very low

Prophylactic CPAP vs mechanical ventilation

Prophylactic CPAP probably leads to lower combined outcome of death and bronchopulmonary dysplasia defined as… compared with mechanical ventilation (moderate certainty).

• Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
  RR 0.89 [0.81, 0.97]
  3 studies · 2358 participants
  Moderate

Prophylactic or very early CPAP vs supportive care

Prophylactic or very early CPAP showed no clear difference in bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency… compared with supportive care (moderate certainty).

• Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
  RR 0.76 [0.51, 1.14]
  3 studies · 683 participants
  Moderate

Prophylactic or very early CPAP vs supportive care

Prophylactic or very early CPAP showed no clear difference in combined outcome of death and bronchopulmonary dysplasia defined as… compared with supportive care (low certainty).

• Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
  RR 0.69 [0.4, 1.19]
  1 study · 256 participants
  Low

Prophylactic CPAP vs mechanical ventilation

Prophylactic CPAP probably leads to lower bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency… compared with mechanical ventilation (moderate certainty).

• Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
  RR 0.89 [0.8, 0.99]
  3 studies · 2150 participants
  Moderate

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 271 participants
  Moderate
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 171 participants
  Low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 234 participants
  Low
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 170 participants
  Low

High levels of PEEP vs low levels of PEEP

• High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 2594 participants
  Low

High levels of PEEP vs low levels of PEEP

• High versus low positive end‐expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute… 2021 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 2309 participants
  Low