Adverse effects of antibiotics: proportion of participants with one or more serious adverse event · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Ciprofloxacin showed no clear difference in adverse effects of antibiotics: proportion of participants with one… compared with placebo added to cycled and culture‐based inhaled tobramycin (TNS)… (moderate certainty).
1 finding from 1 review
Change in visual loss associated with PSR: visual loss is defined by the deterioration of visual acuity of 3 lines or more with the Snellen chart · type 1 or type 2 diabetics
It is very uncertain whether blood pressure intervention/intensive blood pressure intervention changes visual acuity (loss of 3 lines or more) by 5 years compared with placebo/standard blood pressure intervention (very low certainty).
1 finding from 1 review
The proportion of patients with one or more potentially inappropriate medication (PIM) · older people receiving polypharmacy
It is very uncertain whether pharmaceutical care changes the proportion of patients with one or more potentially… compared with usual care (very low certainty).
1 finding from 1 review
The proportion of patients with one or more potential prescribing omission (PPO) · older people receiving polypharmacy
It is very uncertain whether pharmaceutical care changes the proportion of patients with one or more potential prescribing… compared with usual care (very low certainty).
1 finding from 1 review
Patient‐reported pain: at more than 24 months · women with urinary incontinence
Single‐incision slings probably leads to lower patient‐reported pain: at more than 24 months compared with transobturator minimally‐invasive slings (moderate certainty).
1 finding from 1 review
Patient‐reported pain: at more than 24 months · women with urinary incontinence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Patient‐reported pain: at more than 24 months · women with urinary incontinence
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Progression to visual loss (loss of 3 or more lines on logMAR chart) · proliferative diabetic retinopathy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mood disturbance Profile of mood state (higher score indicates more mood disturbance, score range from 0 to 200) · Women with non‐metastatic breast cancer
1 finding from 1 review
Participants with adverse events: 1 or more serious adverse events regardless of type of storage of the vaccine Clinical or laboratory criteria · healthy older adults aged ≥ 60 years
Live zoster vaccine showed no clear difference in participants with adverse events: 1 or more serious adverse events… compared with placebo (moderate certainty).
1 finding from 1 review
Proportion of participants with one or more serious adverse events · Children and adolescents with ADHD
It is very uncertain whether methylphenidate changes proportion of participants with one or more serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Adverse events considered non‐serious (penicillin versus doxycycline) · Children and adolescents with ADHD
It is very uncertain whether methylphenidate changes proportion of participants with one or more adverse events… compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Rate of exacerbations requiring systemic corticosteroids · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more exacerbations treated… compared with placebo (high certainty).
1 finding from 1 review
Patients with severe exacerbations (requiring hospitalisation or ER visit) · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more exacerbations requiring… compared with placebo (moderate certainty).
1 finding from 1 review
Proportion of participants with one or more serious adverse events due to any cause · children and adults with predominantly mild to moderate asthma
Summary of findings table ‐ Vitamin D showed no clear difference in proportion of participants with one or more serious adverse events… compared with placebo (high certainty).
1 finding from 1 review
Prolapse on examination (Stage 2 or above) ‐ Any recurrent prolapse · women with apical vaginal prolapse
Sacral colpopexy: laparoscopic showed no clear difference in prolapse on examination (Stage 2 or more): Any recurrent prolapse compared with alternative approach (low certainty).
1 finding from 1 review
Number of people sustaining one or more fall‐related fractures · Older people living in the community
It is very uncertain whether assistive technology for vision improvement interventions changes number of people who experienced 1 or more fall‐related fractures compared with usual care or attention control (very low certainty).
1 finding from 1 review
Number of people who experienced 1 or more hospitalisations following a fall · Older people living in the community
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of people who experienced one or more falls · Older people living in the community
It is very uncertain whether education interventions changes number of people who experienced 1 or more falls compared with control (e.g. usual care) (very low certainty).
1 finding from 1 review
Number of people sustaining one or more fall‐related fractures · Older people living in the community
Education interventions showed no clear difference in number of people who experienced 1 or more fall‐related fractures compared with control (e.g. usual care) (low certainty).
1 finding from 1 review