Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,087 questions · 2,360 findings · 390 reviews

No studies found 224 · 9.5%GRADE not reported 603 · 25.6%Very low 555 · 23.5%Low 548 · 23.2%Moderate 312 · 13.2%High 118 · 5%

Early discharge vs standard discharge

Number of infants having contact with healthcare professionals regarding infant health issues within 4 weeks of birth · healthy mothers and term infants

Early discharge showed no clear difference in number of infants having contact with healthcare professionals… compared with standard discharge (moderate certainty).

1 finding from 1 review

Early discharge vs standard discharge

Number of women having contact with healthcare professionals regarding maternal health issues within 6 weeks of giving birth · healthy mothers and term infants

Early discharge showed no clear difference in number of women having contact with healthcare professionals… compared with standard discharge (moderate certainty).

1 finding from 1 review

Early treatment vs expectant management

Proportion of infants requiring surgical PDA ligation or transcatheter occlusion · preterm infants

It is very uncertain whether early treatment changes proportion of infants requiring surgical PDA ligation or… compared with expectant management (very low certainty).

1 finding from 1 review

Early treatment vs expectant management

Proportion of infants receiving any pharmacotherapy for a hemodynamically significant PDA · preterm infants

Early treatment may leads to higher proportion of infants receiving any pharmacotherapy for a… compared with expectant management (low certainty).

1 finding from 1 review

Early treatment vs expectant management

Severe intraventricular hemorrhage in infants who received neuroimaging · preterm infants

Early treatment showed no clear difference in severe Intraventricular hemorrhage (grades III and IV) compared with expectant management (low certainty).

1 finding from 1 review

Early ART vs standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl)

Death · patients with asymptomatic, HIV‐infected, treatment naive adults

Early ART probably leads to lower death compared with standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl) (moderate certainty).

1 finding from 1 review

Early ART vs standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl)

Tuberculosis · patients with asymptomatic, HIV‐infected, treatment naive adults

Early ART showed no clear difference in tuberculosis compared with standard or deferred ART (CD4 <= 200 or CD4 <= 250 cells/µl) (moderate certainty).

1 finding from 1 review