Hospitalisation for UTI · adult kidney transplant recipients
Antibiotics showed no clear difference in hospitalisation for UTI compared with no treatment (low certainty).
1 finding from 1 review
Graft function · adult kidney transplant recipients
1 finding from 1 review
Number of participants who were not cured at · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis
Antibiotics showed no clear difference in number of participants who were not cured at compared with placebo or no treatment (low certainty).
1 finding from 1 review
Number of participants rehospitalised for a respiratory illness · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis
Antibiotics showed no clear difference in number of participants rehospitalised for a respiratory illness compared with placebo or no treatment (low certainty).
1 finding from 1 review
Proportion of participants with recurrent wheeze · children < 24 months with ongoing symptoms (cough/wheeze) post‐acute bronchiolitis
Antibiotics showed no clear difference in proportion of participants with recurrent wheeze compared with placebo or no treatment (low certainty).
1 finding from 1 review
Complete resolution of OME at 2 to 3 months · Children with otitis media with effusion
Antibiotics probably leads to higher complete resolution of OME at 2 to 3 months compared with placebo, no treatment or therapy of unproven effectiveness (moderate certainty).
2 findings from 1 review
Adverse effects · Children with otitis media with effusion
Antibiotics may leads to higher adverse effects compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
Complete resolution of OME at more than 6 months · Children with otitis media with effusion
Antibiotics may leads to higher complete resolution of OME at more than 6 months compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
Insertion of ventilation tubes · Children with otitis media with effusion
Antibiotics showed no clear difference in insertion of ventilation tubes compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
Tympanic membrane sequelae · Children with otitis media with effusion
Antibiotics showed no clear difference in tympanic membrane sequelae compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
1 finding from 1 review
Clinical failure rate · patients with uncomplicated acute maxillary sinusitis
Antibiotics probably leads to lower clinical failure rate compared with placebo (moderate certainty).
2 findings from 1 review
Quality of life and activity impairment · patients with uncomplicated acute maxillary sinusitis
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Intrapartum fever needing treatment with antibiotics · women in the second or third trimester of pregnancy before labour and delivery
1 finding from 1 review
Health‐related quality of life · people (of any age) with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Ear pain (otalgia) or discomfort or local irritation · people (of any age) with CSOM
It is very uncertain whether systemic antibiotics changes ear pain (otalgia) or discomfort or local irritation ‐ measured at 1… compared with no treatment or placebo on top of topical antibiotics (very low certainty).
1 finding from 1 review
Hearing · people (of any age) with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious complications ‐ measured at 19 to 24 days · people (of any age) with CSOM
1 finding from 1 review
Suspected ototoxicity · people (of any age) with CSOM
It is very uncertain whether systemic antibiotics changes suspected ototoxicity ‐ measured at 10 days to 3 weeks compared with no treatment or placebo on top of topical antibiotics (very low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured at 1 to 2 weeks · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
1 finding from 1 review