Question · asked by 1 review

Antibiotics vs placebo, no treatment or therapy of unproven effectiveness: Complete resolution of OME at 2 to 3 months

Antibiotics probably leads to higher complete resolution of OME at 2 to 3 months compared with placebo, no treatment or therapy of unproven effectiveness (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Antibiotics vs placebo, no treatment or therapy of unproven effectiveness
Complete resolution of OME at 2 to 3 months · children with otitis media with effusion
Antibiotics probably leads to higher complete resolution of OME at 2 to 3 months compared with placebo, no treatment or therapy of unproven effectiveness (moderate certainty).
Antibiotics for otitis media with effusion in children (2016) · Cochrane Headline outcomes only
RR 2 [1.58, 2.53]6 studies · 484 participantsModerate
Antibiotics vs placebo, no treatment or therapy of unproven effectiveness
Complete resolution of OME at 2 to 4 weeks · children with otitis media with effusion
Antibiotics may leads to higher complete resolution of OME at 2 to 4 weeks compared with placebo, no treatment or therapy of unproven effectiveness (low certainty).
Antibiotics for otitis media with effusion in children (2016) · Cochrane Headline outcomes only
RR 1.98 [1.47, 2.67]14 studies · 2091 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antibiotics for otitis media with effusion in children
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.