Findings

What do systematic reviews say?

3,372 questions · 3,874 findings · 666 reviews

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No studies found 431 · 11.1%GRADE not reported 783 · 20.2%Very low 995 · 25.7%Low 909 · 23.5%Moderate 596 · 15.4%High 160 · 4.1%

Intervention not reported

Symptom intensity, SD units: measured on ESAS, QUAL‐E Symptom Impact Subscale, SDS, RSC, LCS of FACT‐L, HCS of FACT‐Hep. Higher scores indicate higher symptom intensity. · patients with advanced cancer

1 finding from 1 review

Early palliative care for adults with advanced cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 1054 participants
Low

Neuromuscular electrical stimulation + other intervention (e.g. exercise) vs other intervention alone

Knee pain (short term) VAS scale: 0 to 10; higher score = worse pain. · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…

It is very uncertain whether neuromuscular electrical stimulation + other intervention (e.g.… changes knee pain (short term) VAS scale: 0 to 10; higher score = worse pain. compared with same other intervention only (very low certainty).

1 finding from 1 review

Neuromuscular electrical stimulation (NMES) for patellofemoral pain syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 118 participants
Very low

Neuromuscular electrical stimulation + other intervention (e.g. exercise) vs other intervention alone

Knee pain (long term) VAS scale: 0 to 10; higher score = worse pain. · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…

1 finding from 1 review

Neuromuscular electrical stimulation (NMES) for patellofemoral pain syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Neuromuscular electrical stimulation + other intervention (e.g. exercise) vs other intervention alone

Kujala patellofemoral disorders score Scale from: 0 to 100 (higher scores = better function) · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…

1 finding from 1 review

Neuromuscular electrical stimulation (NMES) for patellofemoral pain syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

NMES vs exercise

Knee function (short term) · patients with patellofemoral pain syndrome (symptoms > 4 weeks (1 study); symptoms > 6 weeks (1 study); symptoms > 8 weeks (1 study); not…

It is very uncertain whether neuromuscular electrical stimulation changes knee function (short term) Arpège function scale (0 to 18; higher… compared with exercise (very low certainty).

1 finding from 1 review

Neuromuscular electrical stimulation (NMES) for patellofemoral pain syndrome 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 94 participants
Very low

Individual TF‐CBT vs inactive control (usual care care, attention control, waitlist)

Severity of PTSD symptoms · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 13 participants
Low

Individual TF‐CBT vs EMDR

Severity of PTSD symptoms · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Very low

Individual TF‐CBT vs inactive control (usual care care, attention control, waitlist)

Quality of life: 1. General quality of life · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Individual TF‐CBT vs Brief PTSD psychoeducation

Severity of PTSD symptoms · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 52 participants
Low

Individual TF‐CBT vs Brief PTSD psychoeducation

Quality of life: 1. General quality of life · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 49 participants
Low

Individual TF‐CBT vs inactive control (usual care care, attention control, waitlist)

Symptoms of co‐morbid psychosis: 1. Overall mental state · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 9 participants
Low

Individual TF‐CBT vs inactive control (usual care care, attention control, waitlist)

Anxiety · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 9 participants
Very low

Individual TF‐CBT vs inactive control (usual care care, attention control, waitlist)

Depressive symptoms · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 48 participants
Very low

EMDR vs inactive control (usual care care, attention control, waitlist)

Severity of PTSD symptoms · Adults with co‐morbid PTSD and SMI

1 finding from 1 review

Psychological interventions for post‐traumatic stress disorder (PTSD) in people with severe mental illness 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 83 participants
Very low

Intervention not reported

Anxiety: Trait Anxiety Inventory (STAI‐Y2) A 40‐item, self‐report assessment of anxiety affect. Trait anxiety can be defined as a relatively enduring disposition to feel stress, worry, and discomfort. Score 20‐80; higher scores suggest higher leve... · adults with stroke

1 finding from 1 review

Yoga for stroke rehabilitation 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Very low

Metronidazole vs placebo

Malodour (smell score measured on a scale of 0 to 3 with higher scores indicating a more offensive smell) · treating malignant wounds

1 finding from 1 review

Systemic antibiotics for treating malignant wounds 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 6 participants
Very low

Ocriplasmin injection vs control

Mean change in validated visual function questionnaire score from baseline Score ranges from 0 to 100, higher scores are better visual function · people with symptomatic vitreomacular adhesion

1 finding from 1 review

Ocriplasmin for symptomatic vitreomacular adhesion 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Moderate

Celecoxib vs NSAIDs

Physical function · patients with rheumatoid arthritis

1 finding from 1 review

Celecoxib for rheumatoid arthritis 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 849 participants
Low

Celecoxib vs placebo

Physical function · patients with rheumatoid arthritis

1 finding from 1 review

Celecoxib for rheumatoid arthritis 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 706 participants
Low

Intervention not reported

Health‐related quality of life SF‐36 scale: total score 0‐100, 8 subscales. Higher values mean better health‐related quality of life. · people at risk for development of T2DM

1 finding from 1 review

Dipeptidyl‐peptidase (DPP)‐4 inhibitors and glucagon‐like peptide (GLP)‐1 analogues for prevention or delay of type 2… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 1791 participants
Very low