Food preference · Children and adolescents (general population, aged under 20 years)
Food marketing was associated with increased food preference (pooled SMD, 0.30; combined evidence).
2 findings from 1 review
Dental caries prevalence · European adolescents aged 12 years
Pooled caries prevalence was 0.69 (I² = 100.0%).
1 finding from 1 review
Exposed bone (present versus absent) · Adults (>18 years) with established dry socket following permanent tooth extraction
1 finding from 1 review
PRGF versus Alvogyl (King 2018), exposed bone (% patients): day 3 PRGF 9.1% vs Alvogyl 9.1%; day 7 PRGF 0% vs Alvogyl 22.7% (P<0.05 at day 7)
1 study · 44 participants
GRADE not reported
Acute necrotising ulcerative gingivitis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
Acute necrotising ulcerative gingivitis was significantly more prevalent in treatment-naive CLWH than in those on ART (very low certainty).
1 finding from 1 review
OR 0.00 [0.00, 0.02]
Studies not reported
Very low
Dental caries prevalence measured by dmft or DMFT/S score greater than one · Primary school children (aged 3-16 years) attending primary school in low- and middle-income countries (LMICs)
School-based interventions may reduce the prevalence of dental caries (RR 0.70, favouring intervention), but the certainty of evidence is very low.
2 findings from 1 review
Dental caries prevalence · European adolescents aged 17 years
Pooled caries prevalence was 0.83 (I² = 87.2%).
1 finding from 1 review
Parotid hypertrophy prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
Parotid hypertrophy was significantly more prevalent in treatment-naive CLWH than in those on ART (very low certainty).
1 finding from 1 review
OR 0.01 [0.00, 0.05]
Studies not reported
Very low
Angular cheilitis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No eligible studies compared angular cheilitis between different ART regimens.
1 finding from 1 review
Caries prevalence in permanent dentition · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
A primary-dentition DMFT of 1-3 is associated with 1.5 times higher risk of caries in permanent teeth (single study; not GRADE-rated).
1 finding from 1 review
Recurrent oral ulceration prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in recurrent oral ulceration between ART regimens (very low certainty).
1 finding from 1 review
Dental caries prevalence · European adolescents aged 16 years
Pooled caries prevalence was 0.83.
1 finding from 1 review
Dental caries prevalence · Children or adolescents
In permanent dentition, CLWH on ART had higher caries prevalence than healthy controls (OR 2.49, 95% CI 1.86 to 3.32; single study).
3 findings from 1 review
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review… 2022 All outcomesCross-sectional (case-control; single time point) · HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal) · Permanent dentition (DMFT > 0)
OR 2.49 [1.86, 3.32]
1 study · 724 participants
GRADE not reported
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review… 2022 All outcomesCross-sectional (case-control; single time point) · HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal)
OR 2.70 [2.01, 3.62]
2 studies · 1028 participants
GRADE not reported
Oral Health Status of Children and Adolescents Living with HIV Undergoing Antiretroviral Therapy: A Systematic Review… 2022 All outcomesCross-sectional (case-control; single time point) · HIV pediatric/ART clinics, AIDS centers, and hospitals in Brazil, India, Saudi Arabia, and West Africa (Cote d'Ivoire, Mali, Senegal) · Primary dentition (dmft > 0)
OR 1.93 [1.34, 2.79]
1 study · 564 participants
GRADE not reported
Dental caries prevalence · European adolescents aged 16 years
Pooled caries prevalence was 0.94.
1 finding from 1 review
Mucocele prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in mucocele between CLWH with and without ART (very low certainty).
1 finding from 1 review
OR 0.02 [0.00, 1.09]
Studies not reported
Very low
Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
cART was associated with a significantly lower prevalence of oral candidiasis in CLWH (very low certainty).
1 finding from 1 review
OR 0.35 [0.24, 0.51]
Studies not reported
Very low
Oral candidiasis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
Oral candidiasis prevalence did not differ significantly between treatment-naive CLWH and those on monotherapy or dual therapy (very low certainty).
1 finding from 1 review
Angular cheilitis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
No significant difference in angular cheilitis between CLWH with and without ART (very low certainty).
1 finding from 1 review
OR 0.58 [0.17, 1.99]
Studies not reported
Very low
Ulcerative stomatitis prevalence · Children and adolescents (<18 years) living with HIV (CLWH)
Ulcerative stomatitis was significantly more prevalent in treatment-naive CLWH than in those on ART (very low certainty).
1 finding from 1 review
OR 0.03 [0.02, 0.07]
Studies not reported
Very low
Dental caries prevalence · European adolescents aged 12–19 years
Pooled caries prevalence was 0.74 (I² = 99.9%).
1 finding from 1 review
Caries prevalence in permanent dentition · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)
A primary-dentition DMFT over 13 is associated with about 15 times higher risk of caries in permanent teeth (single study; not GRADE-rated).
1 finding from 1 review