ICS showed no clear difference in FEV1 at 1 hour compared with placebo (low certainty).
ICS showed no clear difference in FEV1 at 3 to 4 hours compared with placebo (moderate certainty).
ICS showed no clear difference in adverse effects ‐ nausea/vomiting compared with placebo (low certainty).
ICS showed no clear difference in hospital admission compared with systemic corticosteroids (low certainty).
PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM probably leads to lower progression to psychosis ‐ by 6 months compared with SPECIALISED TEAM (moderate certainty).
SPECIALISED TEAM probably leads to lower compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).
SPECIALISED TEAM showed no clear difference in compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).
SPECIALISED TEAM showed no clear difference in service use: 2. Not hospitalised ‐ by five years compared with STANDARD CARE (moderate certainty).
SPECIALISED TEAM probably leads to lower social outcomes: 1. Not living independently ‐ by 5 years compared with STANDARD CARE (moderate certainty).
SPECIALISED TEAM showed no clear difference in social outcomes: 2. Not working or in education ‐ by 5 years compared with STANDARD CARE (moderate certainty).
The intervention leads to lower all‐cause mortality at 2 days ‐ immediate treatment (high certainty).
The intervention leads to lower all‐cause mortality at 10 days‐ short‐term treatment (high certainty).
The intervention showed no clear difference in all‐cause mortality at 2 days ‐ immediate treatment (high certainty).
The intervention leads to lower all‐cause mortality at 10 days ‐ short‐term treatment (high certainty).
The intervention showed no clear difference in all‐cause mortality at 2 days ‐ immediate treatment (low certainty).
The intervention showed no clear difference in all‐cause mortality at 10 days ‐ short‐term treatment (high certainty).
It is very uncertain whether the intervention changes all‐cause mortality at 2 days ‐ immediate treatment (very low certainty).
It is very uncertain whether the intervention changes all‐cause mortality at 10 days ‐ short‐term treatment (very low certainty).