Findings

What do systematic reviews say?

4,315 questions · 23,557 findings · 2,311 reviews

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No studies found 4,183 · 17.8%GRADE not reported 3,930 · 16.7%Very low 5,371 · 22.8%Low 5,787 · 24.6%Moderate 3,320 · 14.1%High 966 · 4.1%

Ranked among the 5,000 newest matching findings; add words or filters to narrow the search.

Digital technology (TIM) vs standard treatment (TBM)

FEV1 (% predicted): mean change from baseline · children aged 5 to 16 years

Digital technology (TIM) showed no clear difference in FEV1 (mean change from baseline, % predicted) compared with standard treatment (TBM) (low certainty).

1 finding from 1 review

Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
MD 1
1 study · 20 participants
Low

Digital technology (web‐based platform CFHealthHub) vs usual care

FEV1 % predicted · adults (aged 16 years and over) with CF

Digital technology (web‐based platform CFHealthHub) showed no clear difference in FEV1: mean FEV1 % predicted at end of study compared with usual care (low certainty).

1 finding from 1 review

Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
MD 3.7
1 study · 556 participants
Low

Summary of findings table ‐ Levonorgestrel IUDs vs Copper IUDs

Pregnancy rate · women seeking emergency contraception

1 finding from 1 review

Progestin intrauterine devices versus copper intrauterine devices for emergency contraception 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 638 participants
Very low

Psychological interventions vs usual care

Adherence to inhaled therapies cMPR · children, adolescents or adults with CF

Summary of findings: psychological interventions probably leads to higher adherence to inhaled therapies: % of prescribed inhaled therapies… compared with usual care (moderate certainty).

1 finding from 1 review

Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
MD 9.5 [8.6, 10.4]
1 study · 588 participants
Moderate

Psychological interventions vs active comparators

FEV1 % predicted · adults (aged 16 years and over) with CF

1 finding from 1 review

Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 125 participants
Very low

Psychological interventions vs usual care

Treatment‐related adverse events Depression PHQ‐8 (Kroenke 2009) · children, adolescents or adults with CF

Summary of findings: psychological interventions showed no clear difference in treatment‐related adverse events Depression PHQ‐8 (Kroenke 2009) compared with usual care (low certainty).

1 finding from 1 review

Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 534 participants
Low

Psychological interventions vs usual care

FEV1 % predicted · children, adolescents or adults with CF

Summary of findings: psychological interventions showed no clear difference in lung function FEV1 % predicted compared with usual care (moderate certainty).

1 finding from 1 review

Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
MD 1.4
1 study · 556 participants
Moderate

Psychological interventions vs active comparators

Treatment‐related adverse events Depression · adults (aged 16 years and over) with CF

The review found no eligible studies for this question.

1 finding from 1 review

Psychological interventions for improving adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Donepezil vs placebo

General health and function (Severity of Illness subscale of Clinical Global Impression Scale; lower = better) · children and adolescents with a diagnosis of autism

1 finding from 1 review

Acetylcholinesterase inhibitors for autistic spectrum disorders 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Summary of findings for nasal irrigation with topical steroids plus sinus surgery vs nasal irrigation with topical steroids alone

FEV1 % predicted: absolute change from baseline · children and adults diagnosed with cystic fibrosis and chronic rhinosinusitis with nasal polyposis

1 finding from 1 review

Surgery for nasal polyposis in cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Wearable fitness tracker plus text message for personalized feedback and goal setting vs wearable fitness tracker alone

FEV1 % predicted · adults with CF

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Very low

Web‐based application to record, monitor and set goals on physical activity plus usual care vs usual care

FEV₁: % predicted or L · adolescents and adults with cystic fibrosis

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 63 participants
Low

Web‐based vs face‐to‐face exercise delivery

FEV1 % predicted · children and adults with CF

1 finding from 1 review

Digital technology for delivering and monitoring exercise programs for people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Digital technology vs usual care

FEV1 (% predicted): mean change from baseline · adolescents and adults with cystic fibrosis

1 finding from 1 review

Digital technology for early identification of exacerbations in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 415 participants
Moderate

CBT interventions (CBT with and without exercise) vs control (standard care or sham treatments)

Depression · older adults (mean age minus 1 standard deviation is more than 60 years)

1 finding from 1 review

Cognitive behavioural therapy (CBT) with and without exercise to reduce fear of falling in older people living in the… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 314 participants
Low

Summary of findings table ‐ Sucrose (any concentration, any dose, with or without NNS) vs placebo or control

Pain (PIPP) · neonates

2 findings from 1 review

Sucrose analgesia for heel‐lance procedures in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 547 participants
Moderate
Sucrose analgesia for heel‐lance procedures in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 164 participants
Moderate

Summary of findings table ‐ Sucrose (any concentration, any dose) + NNS vs NNS (with or without water)

PIPP ‐ Preterm infants · neonates

2 findings from 1 review

Sucrose analgesia for heel‐lance procedures in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low
Sucrose analgesia for heel‐lance procedures in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low

Summary of findings table ‐ Sucrose (any concentration, any dose) vs glucose

PIPP ‐ Preterm infants · neonates

2 findings from 1 review

Sucrose analgesia for heel‐lance procedures in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 94 participants
Low
Sucrose analgesia for heel‐lance procedures in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 94 participants
Low

Summary of findings table ‐ Sucrose (any concentration, any dose) vs breastfeeding

Pain (PIPP) · neonates

1 finding from 1 review

Sucrose analgesia for heel‐lance procedures in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 148 participants
Very low

Summary of findings table ‐ Sucrose (any concentration, any dose) vs breastfeeding

COMFORTneo scores after heel lancing (preterm infants)Scale from: 6 to 30e · neonates

1 finding from 1 review

Sucrose analgesia for heel‐lance procedures in neonates 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 47 participants
Very low